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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNL2
All Species:
25.45
Human Site:
S446
Identified Species:
46.67
UniProt:
Q96S94
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S94
NP_001034666.1
520
58147
S446
K
G
S
E
I
R
G
S
R
K
S
K
D
C
K
Chimpanzee
Pan troglodytes
XP_001146359
521
58160
S447
K
G
S
E
I
R
G
S
R
K
S
K
D
C
K
Rhesus Macaque
Macaca mulatta
XP_001093311
520
58157
S446
K
G
S
E
I
R
G
S
R
K
S
K
D
C
K
Dog
Lupus familis
XP_848553
523
58630
Y448
K
G
S
K
V
R
S
Y
R
K
S
K
D
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA7
518
57987
S443
K
G
S
E
V
R
G
S
R
K
S
K
D
C
K
Rat
Rattus norvegicus
Q5I0H5
520
58227
S445
K
G
S
E
V
R
G
S
R
K
S
K
D
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520708
508
57907
K433
G
S
P
H
L
K
A
K
H
A
R
D
D
L
K
Chicken
Gallus gallus
Q5ZJP9
534
59812
Y459
K
S
S
K
M
R
S
Y
K
K
S
K
D
Y
K
Frog
Xenopus laevis
Q6GN15
496
57208
P420
R
H
H
N
H
G
S
P
H
M
K
L
K
H
R
Zebra Danio
Brachydanio rerio
Q7ZVX0
498
57387
D419
S
Q
L
R
T
D
R
D
R
P
S
E
T
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790064
530
60514
K442
P
K
H
R
H
G
H
K
T
K
R
N
R
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWV3
416
47537
R343
D
R
E
R
E
S
D
R
E
K
E
R
G
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
R819
R
Y
S
R
S
P
S
R
S
R
S
R
T
R
S
Conservation
Percent
Protein Identity:
100
99
97.6
91.9
N.A.
89.8
90.3
N.A.
61.1
81
56.5
53
N.A.
N.A.
N.A.
N.A.
48.6
Protein Similarity:
100
99.4
98.2
93.8
N.A.
92.8
93.4
N.A.
74.4
86.1
71.1
68.2
N.A.
N.A.
N.A.
N.A.
63.4
P-Site Identity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
13.3
53.3
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
26.6
73.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.5
N.A.
21.3
Protein Similarity:
N.A.
N.A.
N.A.
46.1
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% C
% Asp:
8
0
0
0
0
8
8
8
0
0
0
8
62
0
0
% D
% Glu:
0
0
8
39
8
0
0
0
8
0
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
47
0
0
0
16
39
0
0
0
0
0
8
0
0
% G
% His:
0
8
16
8
16
0
8
0
16
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
54
8
0
16
0
8
0
16
8
70
8
54
8
0
62
% K
% Leu:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
8
0
0
8
0
8
0
8
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
8
0
31
0
54
8
16
54
8
16
16
8
16
16
% R
% Ser:
8
16
62
0
8
8
31
39
8
0
70
0
0
8
8
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
0
16
8
0
% T
% Val:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
16
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _