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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNL2 All Species: 25.15
Human Site: T292 Identified Species: 46.11
UniProt: Q96S94 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S94 NP_001034666.1 520 58147 T292 A R K K V D L T H L E G E V E
Chimpanzee Pan troglodytes XP_001146359 521 58160 T293 A R K K V D L T H L E G E V E
Rhesus Macaque Macaca mulatta XP_001093311 520 58157 T292 A R K K V D L T H L E G E V E
Dog Lupus familis XP_848553 523 58630 T294 T R K K V D L T H L E S E V E
Cat Felis silvestris
Mouse Mus musculus Q9JJA7 518 57987 T290 T R K K V D L T H L E S E V E
Rat Rattus norvegicus Q5I0H5 520 58227 T290 T R K K V D L T H L E S E V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520708 508 57907 E279 T R K K P N Y E L L E K E V E
Chicken Gallus gallus Q5ZJP9 534 59812 S303 T R K K V D L S D L E S K I E
Frog Xenopus laevis Q6GN15 496 57208 E277 S R I K P N Y E F L E K E V D
Zebra Danio Brachydanio rerio Q7ZVX0 498 57387 E276 S R E K P H S E Q L E R Q V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790064 530 60514 E268 T R K I K S Y E Y L D K K V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWV3 416 47537 Y202 V V A C G V V Y A A A R R F Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RX84 1010 113982 V543 A G Q E A E L V S M I V E S C
Conservation
Percent
Protein Identity: 100 99 97.6 91.9 N.A. 89.8 90.3 N.A. 61.1 81 56.5 53 N.A. N.A. N.A. N.A. 48.6
Protein Similarity: 100 99.4 98.2 93.8 N.A. 92.8 93.4 N.A. 74.4 86.1 71.1 68.2 N.A. N.A. N.A. N.A. 63.4
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 53.3 60 40 40 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 60 80 60 60 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 32.5 N.A. 21.3
Protein Similarity: N.A. N.A. N.A. 46.1 N.A. 32.1
P-Site Identity: N.A. N.A. N.A. 0 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 8 0 8 0 0 0 8 8 8 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 54 0 0 8 0 8 0 0 0 8 % D
% Glu: 0 0 8 8 0 8 0 31 0 0 77 0 70 0 77 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 0 8 0 0 8 0 0 0 0 0 0 24 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 47 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 8 0 0 8 0 % I
% Lys: 0 0 70 77 8 0 0 0 0 0 0 24 16 0 0 % K
% Leu: 0 0 0 0 0 0 62 0 8 85 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 8 % Q
% Arg: 0 85 0 0 0 0 0 0 0 0 0 16 8 0 0 % R
% Ser: 16 0 0 0 0 8 8 8 8 0 0 31 0 8 0 % S
% Thr: 47 0 0 0 0 0 0 47 0 0 0 0 0 0 0 % T
% Val: 8 8 0 0 54 8 8 8 0 0 0 8 0 77 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 24 8 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _