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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHF1
All Species:
26.06
Human Site:
Y74
Identified Species:
52.12
UniProt:
Q96S99
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S99
NP_077286.3
279
31195
Y74
I
V
L
N
K
R
K
Y
R
S
Q
H
I
I
P
Chimpanzee
Pan troglodytes
XP_512558
279
31146
Y74
I
V
L
N
K
R
K
Y
R
S
Q
H
I
I
P
Rhesus Macaque
Macaca mulatta
XP_001084522
279
31261
Y74
I
V
L
N
K
R
K
Y
R
S
Q
H
I
I
P
Dog
Lupus familis
XP_541726
283
31236
Y74
I
V
L
S
K
R
K
Y
R
G
Q
H
I
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TB82
279
31139
Y74
I
V
L
S
K
R
K
Y
R
S
Q
H
I
I
P
Rat
Rattus norvegicus
Q68FU1
279
31422
Y74
I
V
L
S
K
R
K
Y
R
S
Q
H
I
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507289
314
34377
Y74
I
V
L
S
K
R
K
Y
N
G
Q
R
I
I
P
Chicken
Gallus gallus
Q5ZLY5
249
27697
K51
K
L
C
R
K
K
P
K
A
R
Q
F
F
L
F
Frog
Xenopus laevis
NP_001091185
248
27817
P50
T
K
L
C
R
K
K
P
K
A
R
Q
F
F
L
Zebra Danio
Brachydanio rerio
Q7ZUV1
247
27424
R49
L
T
K
L
C
R
K
R
P
K
A
R
Q
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624027
268
29804
V68
I
L
V
Y
G
N
I
V
M
N
K
K
K
Y
N
Nematode Worm
Caenorhab. elegans
P34657
266
30169
V68
I
L
V
Y
G
N
I
V
I
S
K
K
R
Y
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.9
89
N.A.
89.9
90.6
N.A.
69.1
49.4
47.6
50.5
N.A.
N.A.
51.2
44.4
N.A.
Protein Similarity:
100
99.2
98.9
92.9
N.A.
94.2
95.3
N.A.
76.4
63.7
65.9
65.9
N.A.
N.A.
66.6
59.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
73.3
13.3
13.3
13.3
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
80
33.3
46.6
20
N.A.
N.A.
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% A
% Cys:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
17
17
17
% F
% Gly:
0
0
0
0
17
0
0
0
0
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
75
0
0
0
0
0
17
0
9
0
0
0
59
59
0
% I
% Lys:
9
9
9
0
67
17
75
9
9
9
17
17
9
0
0
% K
% Leu:
9
25
67
9
0
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
17
0
0
9
9
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
59
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
67
9
9
0
0
% Q
% Arg:
0
0
0
9
9
67
0
9
50
9
9
17
9
0
0
% R
% Ser:
0
0
0
34
0
0
0
0
0
50
0
0
0
0
0
% S
% Thr:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
59
17
0
0
0
0
17
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
59
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _