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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
20
Human Site:
S448
Identified Species:
36.67
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
S448
H
I
S
Q
L
Q
E
S
I
R
A
E
I
P
C
Chimpanzee
Pan troglodytes
XP_518428
831
92792
S624
H
I
S
Q
L
Q
E
S
I
R
A
E
I
P
C
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
S624
H
I
S
Q
L
Q
E
S
I
R
A
E
I
P
C
Dog
Lupus familis
XP_850330
823
92006
S616
D
I
S
Q
L
Q
E
S
I
R
A
E
I
P
C
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
T448
E
E
S
I
R
A
D
T
P
S
G
D
E
Q
E
Rat
Rattus norvegicus
NP_001020897
655
73837
R448
D
I
T
H
L
Q
E
R
I
R
A
H
T
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
L364
E
A
K
N
A
Q
K
L
K
V
K
I
A
D
L
Chicken
Gallus gallus
XP_419265
754
84415
S549
E
I
S
H
L
Q
E
S
I
R
T
E
M
P
S
Frog
Xenopus laevis
NP_001085122
605
68633
T423
G
S
S
A
M
K
M
T
A
N
T
H
L
L
N
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
D432
S
L
T
A
E
L
K
D
P
R
A
E
M
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
N606
L
V
K
M
A
Q
E
N
M
T
K
N
K
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
K263
V
P
K
S
S
A
I
K
V
I
D
F
G
S
T
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
Y522
S
S
D
T
N
G
P
Y
I
S
N
T
M
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
6.6
53.3
N.A.
6.6
66.6
6.6
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
60
N.A.
13.3
73.3
33.3
46.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
16
16
0
0
8
0
47
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% C
% Asp:
16
0
8
0
0
0
8
8
0
0
8
8
0
16
0
% D
% Glu:
24
8
0
0
8
0
54
0
0
0
0
47
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% G
% His:
24
0
0
16
0
0
0
0
0
0
0
16
0
0
0
% H
% Ile:
0
47
0
8
0
0
8
0
54
8
0
8
31
0
0
% I
% Lys:
0
0
24
0
0
8
16
8
8
0
16
0
8
8
8
% K
% Leu:
8
8
0
0
47
8
0
8
0
0
0
0
8
8
8
% L
% Met:
0
0
0
8
8
0
8
0
8
0
0
0
24
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
0
8
8
8
0
0
8
% N
% Pro:
0
8
0
0
0
0
8
0
16
0
0
0
0
47
0
% P
% Gln:
0
0
0
31
0
62
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
8
0
54
0
0
0
0
0
% R
% Ser:
16
16
54
8
8
0
0
39
0
16
0
0
0
8
24
% S
% Thr:
0
0
16
8
0
0
0
16
0
8
16
8
8
0
8
% T
% Val:
8
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _