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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
43.33
Human Site:
Y559
Identified Species:
79.44
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
Y559
E
P
H
S
G
E
E
Y
T
R
D
E
D
H
I
Chimpanzee
Pan troglodytes
XP_518428
831
92792
Y735
E
P
H
S
G
E
E
Y
T
R
D
E
D
H
I
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
Y735
E
P
H
S
G
E
E
Y
T
R
D
E
D
H
I
Dog
Lupus familis
XP_850330
823
92006
Y727
E
P
H
S
G
E
E
Y
T
R
D
E
D
H
I
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
Y552
E
P
H
S
G
E
D
Y
T
R
D
E
D
H
I
Rat
Rattus norvegicus
NP_001020897
655
73837
Y559
E
P
H
S
G
E
D
Y
T
R
D
E
D
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
L445
H
I
A
L
I
I
E
L
L
G
K
V
P
R
K
Chicken
Gallus gallus
XP_419265
754
84415
Y658
E
P
H
S
G
E
D
Y
S
R
D
E
D
H
I
Frog
Xenopus laevis
NP_001085122
605
68633
Y508
E
P
H
S
G
E
N
Y
S
R
D
E
D
H
I
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
Y544
E
P
H
S
G
E
D
Y
S
R
D
E
D
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
Y810
E
P
H
Q
G
D
N
Y
S
R
D
E
D
H
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
L344
G
P
F
P
Q
Q
M
L
K
K
V
D
R
H
S
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
Y612
E
P
D
E
G
H
S
Y
T
K
D
D
D
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
86.6
86.6
86.6
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
93.3
100
N.A.
N.A.
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
31
0
0
0
85
16
85
0
0
% D
% Glu:
85
0
0
8
0
70
39
0
0
0
0
77
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
85
0
0
0
0
8
0
0
0
0
0
% G
% His:
8
0
77
0
0
8
0
0
0
0
0
0
0
93
0
% H
% Ile:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
77
% I
% Lys:
0
0
0
0
0
0
0
0
8
16
8
0
0
0
8
% K
% Leu:
0
0
0
8
0
0
0
16
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
93
0
8
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
77
0
0
8
8
0
% R
% Ser:
0
0
0
70
0
0
8
0
31
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _