KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC6
All Species:
20
Human Site:
S1068
Identified Species:
40
UniProt:
Q96SB8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB8
NP_001135758.1
1091
126326
S1068
L
I
R
I
L
R
M
S
D
P
E
R
G
Q
T
Chimpanzee
Pan troglodytes
XP_001136387
1091
126280
S1068
L
I
R
I
L
R
M
S
D
P
E
R
G
Q
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532882
1606
180795
S1583
L
I
R
I
L
R
M
S
D
P
E
R
G
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q924W5
1097
127179
S1074
L
I
R
I
L
R
M
S
D
P
E
R
G
Q
T
Rat
Rattus norvegicus
NP_001101484
1097
127259
S1074
L
I
R
I
L
R
M
S
D
P
E
R
G
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505822
579
67328
T557
D
L
K
I
K
R
C
T
V
D
A
E
I
K
D
Chicken
Gallus gallus
XP_419962
1096
127736
L1072
V
S
S
R
I
R
I
L
R
M
Q
D
P
E
R
Frog
Xenopus laevis
Q6P9I7
1128
130494
K1106
L
V
R
I
L
R
M
K
D
P
E
R
G
Q
T
Zebra Danio
Brachydanio rerio
NP_001121806
1090
126266
R1068
L
P
I
N
S
L
I
R
V
L
R
L
N
D
P
Tiger Blowfish
Takifugu rubipres
Q802R8
1090
124790
I1068
S
L
P
E
C
R
R
I
H
I
V
Q
L
N
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794820
1236
142110
H1211
S
V
R
I
T
R
L
H
D
P
E
R
N
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12749
1114
127990
I1091
D
I
G
K
I
A
D
I
D
S
S
G
V
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
63.3
N.A.
90
90.4
N.A.
38.1
59.7
60.5
51.4
45.9
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
N.A.
66.1
N.A.
96.3
96.2
N.A.
44
77.9
76.7
70.3
67
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
6.6
86.6
6.6
6.6
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
40
40
93.3
13.3
20
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
9
0
67
9
0
9
0
9
17
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
59
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
9
50
0
9
% G
% His:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
50
9
67
17
0
17
17
0
9
0
0
9
0
9
% I
% Lys:
0
0
9
9
9
0
0
9
0
0
0
0
0
9
0
% K
% Leu:
59
17
0
0
50
9
9
9
0
9
0
9
9
0
0
% L
% Met:
0
0
0
0
0
0
50
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
17
9
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
59
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
9
0
59
0
% Q
% Arg:
0
0
59
9
0
84
9
9
9
0
9
59
0
0
9
% R
% Ser:
17
9
9
0
9
0
0
42
0
9
9
0
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
50
% T
% Val:
9
17
0
0
0
0
0
0
17
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _