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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC6
All Species:
18.79
Human Site:
T911
Identified Species:
37.58
UniProt:
Q96SB8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB8
NP_001135758.1
1091
126326
T911
D
L
D
S
K
V
R
T
L
K
K
F
I
K
L
Chimpanzee
Pan troglodytes
XP_001136387
1091
126280
T911
D
L
D
S
K
V
R
T
L
K
K
F
I
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532882
1606
180795
T1426
D
L
D
N
K
V
R
T
L
K
R
F
I
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q924W5
1097
127179
T917
D
L
D
N
K
V
R
T
L
R
R
F
I
K
L
Rat
Rattus norvegicus
NP_001101484
1097
127259
T917
D
L
D
S
K
V
R
T
L
R
R
F
I
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505822
579
67328
Y410
S
E
F
R
S
E
M
Y
D
V
R
P
R
A
V
Chicken
Gallus gallus
XP_419962
1096
127736
N918
D
A
N
S
K
V
N
N
L
K
K
F
I
R
V
Frog
Xenopus laevis
Q6P9I7
1128
130494
H949
D
V
E
G
K
V
K
H
L
K
R
F
I
K
L
Zebra Danio
Brachydanio rerio
NP_001121806
1090
126266
G916
K
I
S
R
Q
V
K
G
L
D
A
F
I
H
Q
Tiger Blowfish
Takifugu rubipres
Q802R8
1090
124790
N916
N
K
A
Q
Q
I
K
N
L
N
N
F
I
K
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794820
1236
142110
G1052
K
V
K
K
Q
I
K
G
M
R
R
F
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12749
1114
127990
A927
L
S
Q
E
E
V
I
A
L
F
E
K
C
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
63.3
N.A.
90
90.4
N.A.
38.1
59.7
60.5
51.4
45.9
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
N.A.
66.1
N.A.
96.3
96.2
N.A.
44
77.9
76.7
70.3
67
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
86.6
N.A.
0
60
60
26.6
26.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
80
86.6
46.6
53.3
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% C
% Asp:
59
0
42
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
9
9
9
9
9
0
0
0
0
9
0
0
9
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
9
0
84
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% H
% Ile:
0
9
0
0
0
17
9
0
0
0
0
0
75
0
0
% I
% Lys:
17
9
9
9
59
0
34
0
0
42
25
9
0
59
9
% K
% Leu:
9
42
0
0
0
0
0
0
84
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
9
17
0
0
9
17
0
9
9
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
9
25
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
17
0
0
42
0
0
25
50
0
9
17
0
% R
% Ser:
9
9
9
34
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
75
0
0
0
9
0
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _