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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM209
All Species:
33.33
Human Site:
S145
Identified Species:
56.41
UniProt:
Q96SK2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SK2
NP_116231.2
561
62922
S145
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Chimpanzee
Pan troglodytes
XP_519378
560
62703
S144
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Rhesus Macaque
Macaca mulatta
XP_001094951
644
71948
S228
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Dog
Lupus familis
XP_532426
561
62971
S145
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRG8
561
62963
S145
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Rat
Rattus norvegicus
Q68FR5
561
62895
S145
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510292
628
69659
S212
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Chicken
Gallus gallus
XP_414977
611
68336
T196
A
K
K
V
P
S
S
T
P
S
P
P
I
Q
G
Frog
Xenopus laevis
Q6GPP7
561
63281
S145
N
V
L
S
Y
S
P
S
R
S
P
S
S
S
P
Zebra Danio
Brachydanio rerio
XP_682843
558
62377
A144
N
V
L
S
F
S
P
A
R
P
S
S
T
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730256
538
61543
I135
D
I
E
D
D
I
P
I
I
N
W
H
S
S
F
Honey Bee
Apis mellifera
XP_001122585
493
55278
R89
N
A
L
Y
H
I
T
R
Y
A
W
S
N
F
S
Nematode Worm
Caenorhab. elegans
Q03564
643
72596
A153
S
T
P
I
V
P
D
A
Q
N
V
L
D
T
S
Sea Urchin
Strong. purpuratus
XP_780705
586
65292
C146
P
P
L
S
S
S
P
C
S
V
K
P
P
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
98
N.A.
95.1
94.8
N.A.
78
78.2
75.5
68.9
N.A.
27.6
29
21.4
40.6
Protein Similarity:
100
99.6
86.8
99.4
N.A.
97.1
97.1
N.A.
82.9
83.3
88.4
85.1
N.A.
45.6
45.9
38.5
63.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
20
86.6
66.6
N.A.
13.3
13.3
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
100
86.6
N.A.
33.3
33.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
15
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
8
0
8
0
15
0
8
8
0
0
0
8
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
79
0
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
0
0
0
0
15
0
0
8
0
0
% N
% Pro:
8
8
8
0
8
8
79
0
8
8
65
15
8
0
65
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
65
0
0
0
0
0
0
% R
% Ser:
58
0
0
72
8
79
8
58
8
65
8
72
15
79
15
% S
% Thr:
0
8
0
0
0
0
8
8
0
0
0
0
58
8
0
% T
% Val:
0
65
0
8
8
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
8
58
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _