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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM209
All Species:
26.36
Human Site:
S176
Identified Species:
44.62
UniProt:
Q96SK2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SK2
NP_116231.2
561
62922
S176
L
S
S
G
G
S
G
S
Y
S
P
G
V
T
Y
Chimpanzee
Pan troglodytes
XP_519378
560
62703
S175
L
S
S
G
G
S
G
S
Y
S
P
G
V
T
Y
Rhesus Macaque
Macaca mulatta
XP_001094951
644
71948
S259
L
S
S
G
G
S
G
S
Y
S
P
G
V
T
Y
Dog
Lupus familis
XP_532426
561
62971
S176
L
S
S
G
G
S
G
S
Y
S
P
G
V
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRG8
561
62963
S176
L
S
S
G
G
L
G
S
Y
S
P
G
V
T
Y
Rat
Rattus norvegicus
Q68FR5
561
62895
S176
L
S
S
G
G
L
G
S
Y
S
P
A
V
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510292
628
69659
S243
L
P
S
S
G
S
N
S
F
G
T
A
V
T
Y
Chicken
Gallus gallus
XP_414977
611
68336
P227
K
F
A
T
S
C
I
P
G
Y
S
P
Q
L
Q
Frog
Xenopus laevis
Q6GPP7
561
63281
P176
M
L
P
N
S
G
S
P
F
T
S
V
V
S
Y
Zebra Danio
Brachydanio rerio
XP_682843
558
62377
S175
T
S
S
G
G
P
F
S
P
S
M
S
F
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730256
538
61543
K166
T
R
T
P
Q
Q
T
K
Q
N
T
S
Y
N
S
Honey Bee
Apis mellifera
XP_001122585
493
55278
K120
S
E
D
D
P
F
F
K
N
E
L
P
L
S
Q
Nematode Worm
Caenorhab. elegans
Q03564
643
72596
L184
P
S
F
K
S
S
Q
L
Q
Q
S
P
S
P
N
Sea Urchin
Strong. purpuratus
XP_780705
586
65292
G177
P
S
L
M
G
A
Y
G
S
P
K
L
T
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
98
N.A.
95.1
94.8
N.A.
78
78.2
75.5
68.9
N.A.
27.6
29
21.4
40.6
Protein Similarity:
100
99.6
86.8
99.4
N.A.
97.1
97.1
N.A.
82.9
83.3
88.4
85.1
N.A.
45.6
45.9
38.5
63.6
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
53.3
0
13.3
40
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
60
6.6
40
40
N.A.
13.3
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
8
8
0
0
8
15
0
15
0
0
0
8
0
0
% F
% Gly:
0
0
0
50
65
8
43
8
8
8
0
36
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
15
0
0
8
0
0
0
8
% K
% Leu:
50
8
8
0
0
15
0
8
0
0
8
8
8
8
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
8
8
0
0
0
8
15
% N
% Pro:
15
8
8
8
8
8
0
15
8
8
43
22
0
15
0
% P
% Gln:
0
0
0
0
8
8
8
0
15
8
0
0
8
0
15
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
65
58
8
22
43
8
58
8
50
22
15
8
15
8
% S
% Thr:
15
0
8
8
0
0
8
0
0
8
15
0
8
50
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
43
8
0
0
8
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _