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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM209
All Species:
33.94
Human Site:
S228
Identified Species:
57.44
UniProt:
Q96SK2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SK2
NP_116231.2
561
62922
S228
S
S
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Chimpanzee
Pan troglodytes
XP_519378
560
62703
S227
S
S
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Rhesus Macaque
Macaca mulatta
XP_001094951
644
71948
S311
S
S
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Dog
Lupus familis
XP_532426
561
62971
S228
S
S
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRG8
561
62963
S228
S
P
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Rat
Rattus norvegicus
Q68FR5
561
62895
S228
S
P
P
T
A
Y
N
S
P
T
D
K
E
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510292
628
69659
T295
S
S
P
T
V
Y
N
T
P
T
G
K
E
D
Y
Chicken
Gallus gallus
XP_414977
611
68336
S279
T
S
I
G
P
M
E
S
G
G
L
R
S
R
Y
Frog
Xenopus laevis
Q6GPP7
561
63281
S228
S
S
P
S
A
Y
S
S
P
T
D
K
E
D
Y
Zebra Danio
Brachydanio rerio
XP_682843
558
62377
G227
P
S
V
F
N
S
P
G
G
K
E
D
C
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730256
538
61543
A218
L
T
S
L
M
K
Q
A
D
R
E
R
S
M
M
Honey Bee
Apis mellifera
XP_001122585
493
55278
S172
N
Q
F
F
K
Y
D
S
P
T
S
Q
R
S
A
Nematode Worm
Caenorhab. elegans
Q03564
643
72596
R236
S
N
E
S
I
H
T
R
K
Q
L
D
V
L
L
Sea Urchin
Strong. purpuratus
XP_780705
586
65292
L229
P
A
V
S
S
S
V
L
F
R
D
T
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
98
N.A.
95.1
94.8
N.A.
78
78.2
75.5
68.9
N.A.
27.6
29
21.4
40.6
Protein Similarity:
100
99.6
86.8
99.4
N.A.
97.1
97.1
N.A.
82.9
83.3
88.4
85.1
N.A.
45.6
45.9
38.5
63.6
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
20
80
6.6
N.A.
0
26.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
93.3
33.3
93.3
13.3
N.A.
33.3
46.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
15
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
0
58
15
0
58
8
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
15
0
58
0
0
% E
% Phe:
0
0
8
15
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
15
8
8
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
8
0
0
8
8
0
58
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
8
0
0
15
0
0
8
8
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% M
% Asn:
8
8
0
0
8
0
50
0
0
0
0
0
0
0
0
% N
% Pro:
15
15
58
0
8
0
8
0
65
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
15
0
15
8
8
0
% R
% Ser:
65
58
8
22
8
15
8
65
0
0
8
0
22
8
8
% S
% Thr:
8
8
0
50
0
0
8
8
0
65
0
8
0
0
0
% T
% Val:
0
0
15
0
43
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
65
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _