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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM209
All Species:
29.39
Human Site:
S268
Identified Species:
49.74
UniProt:
Q96SK2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SK2
NP_116231.2
561
62922
S268
P
D
S
T
S
P
S
S
S
P
T
F
W
N
Y
Chimpanzee
Pan troglodytes
XP_519378
560
62703
S267
P
D
S
T
S
P
S
S
S
P
T
F
W
N
Y
Rhesus Macaque
Macaca mulatta
XP_001094951
644
71948
S351
P
D
S
T
S
P
S
S
S
P
T
F
W
N
Y
Dog
Lupus familis
XP_532426
561
62971
T268
P
D
S
T
S
P
S
T
S
P
T
F
W
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRG8
561
62963
T268
P
D
S
T
S
P
S
T
S
P
T
F
W
N
Y
Rat
Rattus norvegicus
Q68FR5
561
62895
T268
P
D
S
T
S
P
S
T
S
P
T
F
W
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510292
628
69659
S335
S
D
S
S
S
P
S
S
S
P
T
F
W
N
Y
Chicken
Gallus gallus
XP_414977
611
68336
K319
F
L
R
S
E
E
E
K
Q
H
R
V
Q
L
G
Frog
Xenopus laevis
Q6GPP7
561
63281
S268
D
A
S
S
T
S
T
S
P
T
F
W
N
Y
S
Zebra Danio
Brachydanio rerio
XP_682843
558
62377
P267
S
T
S
P
R
H
S
P
S
F
W
N
Y
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730256
538
61543
Y258
Y
M
L
K
T
T
I
Y
Q
L
S
P
P
P
A
Honey Bee
Apis mellifera
XP_001122585
493
55278
A212
S
P
L
L
R
R
C
A
Y
Q
V
A
P
I
I
Nematode Worm
Caenorhab. elegans
Q03564
643
72596
A276
G
R
S
G
Q
I
S
A
N
N
T
W
Q
V
S
Sea Urchin
Strong. purpuratus
XP_780705
586
65292
L269
V
I
S
D
E
A
S
L
R
S
Y
L
S
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
98
N.A.
95.1
94.8
N.A.
78
78.2
75.5
68.9
N.A.
27.6
29
21.4
40.6
Protein Similarity:
100
99.6
86.8
99.4
N.A.
97.1
97.1
N.A.
82.9
83.3
88.4
85.1
N.A.
45.6
45.9
38.5
63.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
0
13.3
26.6
N.A.
0
0
20
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
40
33.3
N.A.
13.3
6.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
15
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
50
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
8
50
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
15
8
0
0
0
8
0
8
0
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
8
8
58
0
% N
% Pro:
43
8
0
8
0
50
0
8
8
50
0
8
15
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
15
8
0
0
15
0
0
% Q
% Arg:
0
8
8
0
15
8
0
0
8
0
8
0
0
0
8
% R
% Ser:
22
0
79
22
50
8
72
36
58
8
8
0
8
8
15
% S
% Thr:
0
8
0
43
15
8
8
22
0
8
58
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
15
50
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
8
0
8
0
8
8
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _