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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM209 All Species: 28.18
Human Site: Y203 Identified Species: 47.69
UniProt: Q96SK2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SK2 NP_116231.2 561 62922 Y203 S P S P P S P Y P T T V G P V
Chimpanzee Pan troglodytes XP_519378 560 62703 Y202 S P S P P S P Y P T T V G P V
Rhesus Macaque Macaca mulatta XP_001094951 644 71948 Y286 S P S P P S S Y P T T V G P V
Dog Lupus familis XP_532426 561 62971 Y203 S P S P S S P Y P T T V G P V
Cat Felis silvestris
Mouse Mus musculus Q8BRG8 561 62963 Y203 S L S P S S P Y P T T V G P V
Rat Rattus norvegicus Q68FR5 561 62895 Y203 S L S P S S P Y P T T V G P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510292 628 69659 Y270 S P P S S S P Y P T S I G P L
Chicken Gallus gallus XP_414977 611 68336 T254 I A Y S P G S T Y N K I S N F
Frog Xenopus laevis Q6GPP7 561 63281 Y203 P S P S S P Q Y L S N L G P V
Zebra Danio Brachydanio rerio XP_682843 558 62377 S202 Q S S P P Y P S S L G P A E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730256 538 61543 M193 L S N E S T Y M S P Y A E V R
Honey Bee Apis mellifera XP_001122585 493 55278 M147 C I S L N R R M V P L S S T G
Nematode Worm Caenorhab. elegans Q03564 643 72596 G211 V S V S D T S G I L E D T K G
Sea Urchin Strong. purpuratus XP_780705 586 65292 L204 P S S Q G S F L S I N G H S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 86.8 98 N.A. 95.1 94.8 N.A. 78 78.2 75.5 68.9 N.A. 27.6 29 21.4 40.6
Protein Similarity: 100 99.6 86.8 99.4 N.A. 97.1 97.1 N.A. 82.9 83.3 88.4 85.1 N.A. 45.6 45.9 38.5 63.6
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 60 6.6 26.6 26.6 N.A. 0 6.6 0 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 80 13.3 40 26.6 N.A. 13.3 6.6 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 8 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 15 % F
% Gly: 0 0 0 0 8 8 0 8 0 0 8 8 58 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 8 8 0 15 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % K
% Leu: 8 15 0 8 0 0 0 8 8 15 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 8 15 0 0 8 8 % N
% Pro: 15 36 15 50 36 8 50 0 50 15 0 8 0 58 0 % P
% Gln: 8 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 8 % R
% Ser: 50 36 65 29 43 58 22 8 22 8 8 8 15 8 0 % S
% Thr: 0 0 0 0 0 15 0 8 0 50 43 0 8 8 0 % T
% Val: 8 0 8 0 0 0 0 0 8 0 0 43 0 8 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 8 58 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _