KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM209
All Species:
35.76
Human Site:
Y515
Identified Species:
60.51
UniProt:
Q96SK2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SK2
NP_116231.2
561
62922
Y515
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Chimpanzee
Pan troglodytes
XP_519378
560
62703
Y514
L
I
Y
Q
S
H
V
Y
N
L
P
K
G
R
N
Rhesus Macaque
Macaca mulatta
XP_001094951
644
71948
Y598
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Dog
Lupus familis
XP_532426
561
62971
Y515
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRG8
561
62963
Y515
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Rat
Rattus norvegicus
Q68FR5
561
62895
Y515
L
I
Y
Q
R
H
V
Y
S
L
P
K
G
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510292
628
69659
Y582
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Chicken
Gallus gallus
XP_414977
611
68336
C562
T
S
N
E
N
V
F
C
I
Y
Q
S
S
I
N
Frog
Xenopus laevis
Q6GPP7
561
63281
Y514
L
V
Y
Q
K
H
I
Y
S
L
P
K
G
R
N
Zebra Danio
Brachydanio rerio
XP_682843
558
62377
Y512
L
V
Y
Q
G
H
V
Y
S
L
P
K
G
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730256
538
61543
V495
D
K
E
L
H
N
C
V
Y
D
R
N
N
L
F
Honey Bee
Apis mellifera
XP_001122585
493
55278
N450
E
E
I
Q
R
G
R
N
N
L
F
H
T
F
L
Nematode Worm
Caenorhab. elegans
Q03564
643
72596
H588
P
P
H
A
E
F
V
H
I
D
E
N
G
Y
A
Sea Urchin
Strong. purpuratus
XP_780705
586
65292
D541
I
L
G
D
D
T
W
D
L
P
K
G
R
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
98
N.A.
95.1
94.8
N.A.
78
78.2
75.5
68.9
N.A.
27.6
29
21.4
40.6
Protein Similarity:
100
99.6
86.8
99.4
N.A.
97.1
97.1
N.A.
82.9
83.3
88.4
85.1
N.A.
45.6
45.9
38.5
63.6
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
100
6.6
73.3
80
N.A.
0
26.6
13.3
6.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
13.3
100
93.3
N.A.
6.6
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
8
0
15
0
0
0
0
0
% D
% Glu:
8
8
8
8
8
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
8
0
8
8
0
0
0
0
0
8
72
0
0
% G
% His:
0
0
8
0
8
65
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
50
8
0
0
0
8
0
15
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
8
65
0
0
0
% K
% Leu:
65
8
0
8
0
0
0
0
8
72
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
8
50
0
0
15
8
8
79
% N
% Pro:
8
8
0
0
0
0
0
0
0
8
65
0
0
0
0
% P
% Gln:
0
0
0
72
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
8
0
0
0
8
0
8
65
0
% R
% Ser:
0
8
0
0
8
0
0
0
22
0
0
8
8
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% T
% Val:
0
15
0
0
0
8
65
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
0
0
0
0
65
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _