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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRC2
All Species:
21.21
Human Site:
S219
Identified Species:
46.67
UniProt:
Q96SL1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SL1
NP_116228.1
478
52088
S219
S
P
L
L
A
A
E
S
S
R
A
H
I
K
D
Chimpanzee
Pan troglodytes
XP_001167764
478
52129
S219
S
P
L
L
A
A
E
S
S
R
A
H
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001116986
162
17240
Dog
Lupus familis
XP_535764
606
65122
T347
S
P
L
L
A
S
E
T
S
R
T
H
I
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFQ6
478
51891
S219
A
P
L
L
A
A
E
S
S
R
A
H
I
K
D
Rat
Rattus norvegicus
Q66H95
478
52012
S219
A
P
L
L
T
A
E
S
S
R
D
H
I
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520694
392
42196
F150
E
M
V
L
D
A
E
F
A
F
V
C
L
I
F
Chicken
Gallus gallus
XP_422095
524
57309
S265
H
L
S
L
L
S
Q
S
N
T
E
H
I
K
D
Frog
Xenopus laevis
Q6GNV7
456
49933
G197
S
G
L
L
L
Y
S
G
S
T
D
A
I
K
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01735
586
63808
T312
N
G
S
V
E
H
V
T
Y
D
L
N
T
L
F
Sea Urchin
Strong. purpuratus
XP_789273
540
59515
V268
N
P
A
D
Y
D
P
V
E
I
Q
H
C
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
33
73.7
N.A.
94.9
94.3
N.A.
69.2
76.9
75.5
N.A.
N.A.
N.A.
N.A.
21.3
34.2
Protein Similarity:
100
99.7
33.8
75.4
N.A.
96.4
96
N.A.
74.4
82
83.2
N.A.
N.A.
N.A.
N.A.
38.7
49.8
P-Site Identity:
100
100
0
80
N.A.
93.3
80
N.A.
20
40
46.6
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
0
93.3
N.A.
100
86.6
N.A.
40
60
46.6
N.A.
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
10
0
37
46
0
0
10
0
28
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
0
0
0
10
10
10
0
0
0
10
19
0
0
0
64
% D
% Glu:
10
0
0
0
10
0
55
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
19
% F
% Gly:
0
19
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
64
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
64
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% K
% Leu:
0
10
55
73
19
0
0
0
0
0
10
0
10
19
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
55
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
10
% R
% Ser:
37
0
19
0
0
19
10
46
55
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
19
0
19
10
0
10
0
0
% T
% Val:
0
0
10
10
0
0
10
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _