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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRC2
All Species:
26.97
Human Site:
Y471
Identified Species:
59.33
UniProt:
Q96SL1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SL1
NP_116228.1
478
52088
Y471
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Chimpanzee
Pan troglodytes
XP_001167764
478
52129
Y471
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Rhesus Macaque
Macaca mulatta
XP_001116986
162
17240
Dog
Lupus familis
XP_535764
606
65122
Y599
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFQ6
478
51891
Y471
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Rat
Rattus norvegicus
Q66H95
478
52012
Y471
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520694
392
42196
Chicken
Gallus gallus
XP_422095
524
57309
Y517
R
E
S
Y
D
R
L
Y
L
D
V
V
V
S
V
Frog
Xenopus laevis
Q6GNV7
456
49933
Y449
R
E
S
Y
D
R
L
Y
L
D
V
F
V
S
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01735
586
63808
R558
F
I
R
E
D
L
K
R
Q
K
A
H
S
V
Q
Sea Urchin
Strong. purpuratus
XP_789273
540
59515
K516
Y
K
E
H
Y
V
R
K
E
F
D
V
T
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
33
73.7
N.A.
94.9
94.3
N.A.
69.2
76.9
75.5
N.A.
N.A.
N.A.
N.A.
21.3
34.2
Protein Similarity:
100
99.7
33.8
75.4
N.A.
96.4
96
N.A.
74.4
82
83.2
N.A.
N.A.
N.A.
N.A.
38.7
49.8
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
100
93.3
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
0
100
93.3
N.A.
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
73
0
0
0
0
64
10
0
0
0
0
% D
% Glu:
0
64
10
10
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
10
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
64
0
64
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
64
0
10
0
0
64
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
64
0
0
0
0
0
0
0
0
0
10
64
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
64
64
64
10
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
64
10
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _