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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORAI2
All Species:
18.18
Human Site:
S135
Identified Species:
40
UniProt:
Q96SN7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SN7
NP_001119812.1
254
28570
S135
I
H
N
L
N
S
I
S
E
S
P
H
E
R
M
Chimpanzee
Pan troglodytes
XP_528664
301
32521
K161
V
H
N
L
N
S
V
K
E
S
P
H
E
R
M
Rhesus Macaque
Macaca mulatta
XP_001108554
254
28554
S135
I
H
N
L
N
S
I
S
E
S
P
H
E
R
M
Dog
Lupus familis
XP_850105
254
28514
S135
I
H
N
L
N
S
I
S
E
S
P
H
E
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH10
250
28180
S135
I
H
N
L
N
S
I
S
E
S
P
H
E
R
M
Rat
Rattus norvegicus
Q5M848
304
33021
K162
V
H
N
L
N
S
V
K
E
S
P
H
E
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507478
312
32775
H137
I
H
N
L
N
S
V
H
Q
S
P
H
Q
R
L
Chicken
Gallus gallus
Q5ZLW2
257
28936
S136
I
H
N
L
N
S
I
S
E
S
P
H
E
R
M
Frog
Xenopus laevis
Q6NZI6
257
28909
N135
I
H
N
L
N
S
V
N
E
S
P
H
D
R
M
Zebra Danio
Brachydanio rerio
Q6TLE6
222
24614
L133
F
L
A
G
V
V
L
L
C
W
V
K
F
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6B8
351
38488
H233
L
H
S
I
S
L
V
H
E
S
P
H
E
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
98.8
98
N.A.
95.2
55.9
N.A.
53.8
88.7
82.4
62.2
N.A.
33
N.A.
N.A.
N.A.
Protein Similarity:
100
67.1
99.6
98.8
N.A.
97.2
66.7
N.A.
64.4
92.2
90.6
71.6
N.A.
45
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
80
N.A.
66.6
100
80
0
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
93.3
100
100
6.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
82
0
0
0
73
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
91
0
0
0
0
0
19
0
0
0
91
0
0
0
% H
% Ile:
64
0
0
10
0
0
46
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
0
10
0
0
0
% K
% Leu:
10
10
0
82
0
10
10
10
0
0
0
0
0
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
73
% M
% Asn:
0
0
82
0
82
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% R
% Ser:
0
0
10
0
10
82
0
46
0
91
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
10
10
46
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _