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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP2
All Species:
4.55
Human Site:
S1368
Identified Species:
12.5
UniProt:
Q96SN8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SN8
NP_001011649.1
1893
215024
S1368
D
Y
E
T
S
E
K
S
F
F
S
R
D
Q
K
Chimpanzee
Pan troglodytes
Q19UN5
1893
214874
S1368
D
Y
E
T
S
E
K
S
F
F
S
Q
D
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855524
1859
208670
A1352
P
E
S
P
E
P
S
A
S
H
A
L
S
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8K389
1822
205926
F1303
D
S
C
V
A
E
G
F
R
E
Q
L
T
Q
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90631
1364
155958
K866
V
S
I
T
S
Q
V
K
E
L
Q
T
L
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687560
1559
174686
L1061
T
L
R
S
E
L
D
L
T
R
S
I
I
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54623
1320
149502
Q822
K
R
R
S
S
E
G
Q
R
K
E
R
R
S
L
Honey Bee
Apis mellifera
XP_392107
1375
159683
R877
D
N
P
V
K
K
S
R
S
E
N
L
I
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791309
2356
267481
M1692
E
V
I
R
S
Q
E
M
E
I
G
R
L
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
71.4
N.A.
68.4
N.A.
N.A.
N.A.
20
N.A.
22.3
N.A.
21.1
22.5
N.A.
21.8
Protein Similarity:
100
99.2
N.A.
80.6
N.A.
78.1
N.A.
N.A.
N.A.
38.6
N.A.
39.8
N.A.
39.3
39.6
N.A.
40.3
P-Site Identity:
100
93.3
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
20
N.A.
6.6
N.A.
20
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
26.6
N.A.
20
N.A.
26.6
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
12
0
0
12
0
0
0
12
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
23
% C
% Asp:
45
0
0
0
0
0
12
0
0
0
0
0
23
12
0
% D
% Glu:
12
12
23
0
23
45
12
0
23
23
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
12
23
23
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
23
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
12
% H
% Ile:
0
0
23
0
0
0
0
0
0
12
0
12
23
0
0
% I
% Lys:
12
0
0
0
12
12
23
12
0
12
0
0
0
12
34
% K
% Leu:
0
12
0
0
0
12
0
12
0
12
0
34
23
12
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
12
0
12
12
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
23
0
12
0
0
23
12
0
34
0
% Q
% Arg:
0
12
23
12
0
0
0
12
23
12
0
34
12
0
0
% R
% Ser:
0
23
12
23
56
0
23
23
23
0
34
0
12
23
0
% S
% Thr:
12
0
0
34
0
0
0
0
12
0
0
12
12
0
0
% T
% Val:
12
12
0
23
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _