KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IWS1
All Species:
18.79
Human Site:
S222
Identified Species:
31.79
UniProt:
Q96ST2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST2
NP_060439.2
819
91955
S222
E
L
P
K
P
Q
V
S
D
S
E
S
E
E
P
Chimpanzee
Pan troglodytes
XP_001139705
1089
121835
S492
E
L
P
K
P
Q
V
S
D
S
E
S
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001087787
827
93220
S222
E
L
P
K
P
Q
V
S
D
S
E
S
E
E
P
Dog
Lupus familis
XP_533312
832
93567
S222
E
L
P
K
P
R
V
S
D
S
E
S
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1D8
766
85230
D210
P
P
R
P
Q
A
S
D
S
E
S
E
E
L
P
Rat
Rattus norvegicus
Q3SWT4
764
85429
Q207
S
E
D
P
P
R
P
Q
V
S
D
S
E
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510535
927
102715
G315
D
N
E
D
P
R
K
G
P
A
S
D
S
D
I
Chicken
Gallus gallus
XP_422571
689
77823
S133
D
A
L
N
H
Q
G
S
D
S
E
N
G
E
P
Frog
Xenopus laevis
Q6DE96
836
92684
S244
A
P
A
K
R
K
V
S
S
S
E
D
E
T
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097000
820
90557
G224
G
S
R
R
S
R
S
G
S
K
Q
S
R
S
G
Honey Bee
Apis mellifera
XP_624549
770
87091
P214
S
H
S
P
S
A
S
P
K
V
A
I
R
S
R
Nematode Worm
Caenorhab. elegans
Q19375
511
57235
Sea Urchin
Strong. purpuratus
XP_798740
798
90991
D225
D
V
D
E
D
E
E
D
E
I
Q
R
Q
H
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06505
410
46064
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.3
93.8
N.A.
84.7
82.4
N.A.
69.6
65
60.4
N.A.
N.A.
26.5
30.1
22.7
31.5
Protein Similarity:
100
74.8
96.1
95.3
N.A.
88.4
87.1
N.A.
75.8
73.7
72.9
N.A.
N.A.
46.7
48.8
37.3
50.9
P-Site Identity:
100
100
100
93.3
N.A.
13.3
26.6
N.A.
6.6
46.6
46.6
N.A.
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
40
N.A.
33.3
60
53.3
N.A.
N.A.
26.6
0
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
15
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
15
8
8
0
0
15
36
0
8
15
0
8
0
% D
% Glu:
29
8
8
8
0
8
8
0
8
8
43
8
50
36
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
15
0
0
0
0
8
0
8
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% I
% Lys:
0
0
0
36
0
8
8
0
8
8
0
0
0
0
0
% K
% Leu:
0
29
8
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
15
29
22
43
0
8
8
8
0
0
0
0
0
50
% P
% Gln:
0
0
0
0
8
29
0
8
0
0
15
0
8
0
8
% Q
% Arg:
0
0
15
8
8
29
0
0
0
0
0
8
15
0
8
% R
% Ser:
15
8
8
0
15
0
22
43
22
50
15
43
8
22
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
36
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _