KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRBN
All Species:
20.61
Human Site:
S434
Identified Species:
37.78
UniProt:
Q96SW2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SW2
NP_057386.2
442
50546
S434
P
D
T
E
D
E
I
S
P
D
K
V
I
L
C
Chimpanzee
Pan troglodytes
XP_001140181
383
43891
T376
N
L
I
G
R
P
S
T
E
H
S
W
F
P
G
Rhesus Macaque
Macaca mulatta
XP_001100581
442
50550
S434
P
D
T
E
D
E
I
S
P
D
K
V
I
L
C
Dog
Lupus familis
XP_533757
444
50959
S436
P
D
T
E
D
E
I
S
P
D
K
V
I
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7D2
445
50862
S437
P
E
T
E
D
E
I
S
P
D
K
V
I
L
C
Rat
Rattus norvegicus
Q56AP7
445
50859
S437
P
E
T
E
D
E
I
S
P
D
K
V
I
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506395
672
76120
D421
P
E
T
E
D
E
T
D
H
V
V
V
S
D
G
Chicken
Gallus gallus
P0CF65
445
51100
G436
P
E
A
E
D
E
L
G
H
D
R
S
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q68EH9
431
49076
E424
P
Q
G
E
E
G
V
E
G
S
R
L
L
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH36
585
66434
N567
A
S
E
Y
S
P
F
N
G
T
T
Y
V
V
R
Honey Bee
Apis mellifera
XP_395264
404
46327
L395
P
K
A
F
W
G
L
L
R
K
S
L
K
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783498
893
103803
S560
Q
E
K
I
D
Q
L
S
K
E
I
D
F
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132097
564
63617
R550
P
R
S
F
W
G
I
R
S
S
Q
I
A
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
99.3
97
N.A.
95.2
95.2
N.A.
55.6
84.2
N.A.
69
N.A.
21
35.5
N.A.
22.6
Protein Similarity:
100
86.6
99.7
97.9
N.A.
97.7
97.7
N.A.
60.2
91.9
N.A.
82.8
N.A.
38.2
52.4
N.A.
33.7
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
40
40
N.A.
13.3
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
46.6
60
N.A.
46.6
N.A.
20
20
N.A.
46.6
Percent
Protein Identity:
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
39
% C
% Asp:
0
24
0
0
62
0
0
8
0
47
0
8
0
16
8
% D
% Glu:
0
39
8
62
8
54
0
8
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
16
0
0
8
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
8
8
0
24
0
8
16
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
47
0
0
0
8
8
39
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
8
8
39
0
8
0
8
% K
% Leu:
0
8
0
0
0
0
24
8
0
0
0
16
8
47
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
77
0
0
0
0
16
0
0
39
0
0
0
8
8
0
% P
% Gln:
8
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
8
8
0
16
0
0
0
8
% R
% Ser:
0
8
8
0
8
0
8
47
8
16
16
8
8
8
0
% S
% Thr:
0
0
47
0
0
0
8
8
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
8
47
8
8
0
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _