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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADO All Species: 22.42
Human Site: S237 Identified Species: 37.95
UniProt: Q96SZ5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SZ5 NP_116193.2 270 29751 S237 R P K E A S S S A C D L P R E
Chimpanzee Pan troglodytes XP_001161814 239 25673 S206 R P K E A S S S A C D L P R E
Rhesus Macaque Macaca mulatta XP_001092839 270 29687 S237 R P K E A S S S A C D L P R E
Dog Lupus familis XP_546121 270 29604 S237 R D K E A S S S A C D L P R E
Cat Felis silvestris
Mouse Mus musculus Q6PDY2 256 28354 S223 R P K E A S G S A C D L P R E
Rat Rattus norvegicus NP_001101096 256 28430 S223 K P K E A S G S A C D L P R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510462 264 28452 A231 A D K E A G A A A A V V P R E
Chicken Gallus gallus
Frog Xenopus laevis NP_001088077 259 27370 A226 A A A S D N C A G G A A Q K E
Zebra Danio Brachydanio rerio NP_998358 249 27467 S216 S E A A D K K S E V Q D Q G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648176 240 27230 P206 Q L H C I P S P D T Y Y C D V
Honey Bee Apis mellifera XP_001120557 231 26005 D199 G S S E L C T D S P D I V E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787160 257 28739 P222 K E L K S L Q P S S S E S D P
Poplar Tree Populus trichocarpa XP_002325431 275 30753 K239 S N G E M E L K K E E G S C Y
Maize Zea mays NP_001130184 276 30043 P227 A V L D V M G P P Y N R A Q G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 98.5 92.9 N.A. 86.6 85.1 N.A. 65.1 N.A. 52.9 54.4 N.A. 27.4 30 N.A. 34.4
Protein Similarity: 100 70.7 98.8 96.3 N.A. 89.6 88.8 N.A. 73.3 N.A. 66.6 67.4 N.A. 45.5 47 N.A. 52.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 46.6 N.A. 6.6 6.6 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 66.6 N.A. 26.6 13.3 N.A. 13.3 40 N.A. 26.6
Percent
Protein Identity: 28.3 31.5 N.A. N.A. N.A. N.A.
Protein Similarity: 44.3 45.6 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 15 8 50 0 8 15 50 8 8 8 8 0 0 % A
% Cys: 0 0 0 8 0 8 8 0 0 43 0 0 8 8 0 % C
% Asp: 0 15 0 8 15 0 0 8 8 0 50 8 0 15 8 % D
% Glu: 0 15 0 65 0 8 0 0 8 8 8 8 0 8 65 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 8 22 0 8 8 0 8 0 8 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 15 0 50 8 0 8 8 8 8 0 0 0 0 8 0 % K
% Leu: 0 8 15 0 8 8 8 0 0 0 0 43 0 0 0 % L
% Met: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 36 0 0 0 8 0 22 8 8 0 0 50 0 8 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 8 0 15 8 0 % Q
% Arg: 36 0 0 0 0 0 0 0 0 0 0 8 0 50 0 % R
% Ser: 15 8 8 8 8 43 36 50 15 8 8 0 15 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % T
% Val: 0 8 0 0 8 0 0 0 0 8 8 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _