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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
9.09
Human Site:
S132
Identified Species:
14.29
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S132
K
S
G
Y
L
R
T
S
N
L
Q
E
A
D
V
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
N130
K
A
E
Q
T
I
W
N
R
L
H
Q
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
N130
K
A
E
Q
T
I
W
N
R
L
H
Q
L
K
A
Dog
Lupus familis
XP_534385
583
65796
R128
K
S
G
Y
L
R
T
R
N
L
Q
E
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
S131
K
S
G
Y
L
R
T
S
N
L
Q
E
A
D
V
Rat
Rattus norvegicus
Q9JLH6
586
65848
S129
K
S
G
Y
L
R
T
S
N
L
Q
E
A
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
E127
C
S
V
R
D
K
A
E
Q
T
I
W
N
R
L
Frog
Xenopus laevis
NP_001090499
565
63917
A132
T
C
S
V
R
E
K
A
E
Q
T
I
W
N
R
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
Q143
S
I
R
E
K
A
E
Q
T
I
W
N
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
L134
E
E
A
D
V
I
M
L
V
T
C
A
V
R
D
Honey Bee
Apis mellifera
XP_393868
618
71037
E164
S
H
G
Y
K
K
V
E
D
I
K
E
A
N
I
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
R127
L
L
M
T
C
S
I
R
D
G
A
E
K
K
V
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
L132
E
V
P
L
K
I
G
L
L
G
C
M
A
E
R
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
V146
N
A
G
Y
S
E
I
V
D
V
P
E
S
A
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
V161
N
S
G
Y
K
E
V
V
T
D
P
E
S
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
13.3
13.3
93.3
N.A.
100
100
N.A.
N.A.
6.6
0
0
N.A.
0
26.6
13.3
6.6
P-Site Similarity:
100
33.3
33.3
93.3
N.A.
100
100
N.A.
N.A.
20
13.3
6.6
N.A.
13.3
66.6
20
20
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
7
0
0
7
7
7
0
0
7
7
40
14
14
% A
% Cys:
7
7
0
0
7
0
0
0
0
0
14
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
20
7
0
0
0
27
7
% D
% Glu:
14
7
14
7
0
20
7
14
7
0
0
54
0
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
47
0
0
0
7
0
0
14
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
14
0
0
0
0
% H
% Ile:
0
7
0
0
0
27
14
0
0
14
7
7
0
0
7
% I
% Lys:
40
0
0
0
27
14
7
0
0
0
7
0
7
20
7
% K
% Leu:
7
7
0
7
27
0
0
14
7
40
0
0
14
7
7
% L
% Met:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
14
27
0
0
7
7
14
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
14
0
0
0
0
% P
% Gln:
0
0
0
14
0
0
0
7
7
7
27
14
0
0
0
% Q
% Arg:
0
0
7
7
7
27
0
14
14
0
0
0
7
14
14
% R
% Ser:
14
40
7
0
7
7
0
20
0
0
0
0
14
0
0
% S
% Thr:
7
0
0
7
14
0
27
0
14
14
7
0
0
0
0
% T
% Val:
0
7
7
7
7
0
14
14
7
7
0
0
7
0
34
% V
% Trp:
0
0
0
0
0
0
14
0
0
0
7
7
7
0
0
% W
% Tyr:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _