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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
14.85
Human Site:
S172
Identified Species:
23.33
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S172
L
K
T
R
R
P
R
S
R
V
P
L
R
I
G
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
K170
E
E
I
L
N
R
E
K
M
V
D
I
L
A
G
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
K170
E
E
I
L
N
R
E
K
M
V
D
V
L
A
G
Dog
Lupus familis
XP_534385
583
65796
S168
L
K
T
K
R
L
R
S
R
V
P
L
R
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
S171
L
K
T
K
R
P
R
S
R
V
P
L
R
I
G
Rat
Rattus norvegicus
Q9JLH6
586
65848
S169
L
K
A
K
R
P
R
S
R
V
P
L
R
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
I167
A
E
R
L
K
E
E
I
L
H
R
E
K
L
V
Frog
Xenopus laevis
NP_001090499
565
63917
I172
A
E
R
L
K
Q
E
I
L
E
R
E
N
L
V
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
L183
E
R
L
K
S
E
L
L
D
Q
E
K
L
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
G174
P
L
Q
L
T
L
L
G
C
M
A
E
R
L
K
Honey Bee
Apis mellifera
XP_393868
618
71037
N204
L
R
K
K
K
K
K
N
P
I
K
I
G
L
L
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
L167
E
R
V
R
H
D
L
L
E
K
R
N
L
V
N
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
S172
R
L
L
N
V
A
G
S
G
Q
T
A
I
N
V
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
S186
F
L
K
R
H
W
K
S
N
V
A
I
G
R
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
V201
F
L
K
R
E
W
K
V
N
A
A
T
G
R
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
13.3
13.3
86.6
N.A.
93.3
86.6
N.A.
N.A.
0
0
0
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
26.6
26.6
93.3
N.A.
100
93.3
N.A.
N.A.
26.6
20
20
N.A.
20
60
20
6.6
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
0
7
0
0
0
7
20
7
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
7
0
14
0
0
0
7
% D
% Glu:
27
27
0
0
7
14
27
0
7
7
7
20
0
0
0
% E
% Phe:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
7
0
0
0
20
0
40
% G
% His:
0
0
0
0
14
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
0
0
14
0
7
0
20
7
27
0
% I
% Lys:
0
27
20
34
20
7
20
14
0
7
7
7
7
0
7
% K
% Leu:
34
27
14
34
0
14
20
14
14
0
0
27
27
27
7
% L
% Met:
0
0
0
0
0
0
0
0
14
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
14
0
0
7
14
0
0
7
7
7
7
% N
% Pro:
7
0
0
0
0
20
0
0
7
0
27
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
0
0
14
0
0
0
0
0
% Q
% Arg:
7
20
14
27
27
14
27
0
27
0
20
0
34
14
0
% R
% Ser:
0
0
0
0
7
0
0
40
0
0
0
0
0
0
7
% S
% Thr:
0
0
20
0
7
0
0
0
0
0
7
7
0
0
0
% T
% Val:
0
0
7
0
7
0
0
7
0
47
0
7
0
14
20
% V
% Trp:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _