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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
1.21
Human Site:
S35
Identified Species:
1.9
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S35
R
M
C
R
A
H
S
S
L
S
S
T
M
C
P
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
L33
D
L
P
A
E
L
R
L
R
D
P
G
H
C
C
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
L33
D
L
P
A
E
L
T
L
R
D
P
G
H
C
C
Dog
Lupus familis
XP_534385
583
65796
S31
L
R
T
C
R
A
L
S
N
L
P
S
T
A
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
V34
T
C
R
A
Q
S
S
V
S
S
T
P
C
P
S
Rat
Rattus norvegicus
Q9JLH6
586
65848
N32
L
R
T
F
R
A
H
N
S
T
S
C
P
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
G30
A
V
R
A
A
H
R
G
Q
S
E
R
P
Q
G
Frog
Xenopus laevis
NP_001090499
565
63917
E35
E
T
L
K
K
K
E
E
L
I
S
R
L
S
T
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
M46
G
T
G
L
S
R
I
M
Q
L
K
S
K
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
S37
S
A
A
G
Q
L
K
S
E
P
A
A
R
A
T
Honey Bee
Apis mellifera
XP_393868
618
71037
Q67
Y
H
N
F
Q
Q
C
Q
T
L
H
A
T
V
I
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
K30
C
S
T
S
A
A
V
K
P
K
R
A
I
P
T
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
R35
T
E
V
E
V
P
V
R
D
D
C
I
P
Y
L
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
N49
K
G
P
L
K
K
R
N
C
S
L
T
L
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
Q64
S
S
T
H
R
L
T
Q
K
P
I
N
R
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
N.A.
20
13.3
0
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
13.3
20
13.3
N.A.
20
26.6
N.A.
N.A.
26.6
26.6
13.3
N.A.
13.3
0
13.3
0
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
27
20
20
0
0
0
0
7
20
0
14
0
% A
% Cys:
7
7
7
7
0
0
7
0
7
0
7
7
7
20
20
% C
% Asp:
14
0
0
0
0
0
0
0
7
20
0
0
0
7
0
% D
% Glu:
7
7
0
7
14
0
7
7
7
0
7
0
0
0
0
% E
% Phe:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
7
0
0
0
7
0
0
0
14
0
0
7
% G
% His:
0
7
0
7
0
14
7
0
0
0
7
0
14
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
7
7
7
7
0
7
% I
% Lys:
7
0
0
7
14
14
7
7
7
7
7
0
7
7
7
% K
% Leu:
14
14
7
14
0
27
7
14
14
20
7
0
14
7
7
% L
% Met:
0
7
0
0
0
0
0
7
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
14
7
0
0
7
0
0
0
% N
% Pro:
0
0
20
0
0
7
0
0
7
14
20
7
20
14
14
% P
% Gln:
0
0
0
0
20
7
0
14
14
0
0
0
0
7
0
% Q
% Arg:
7
14
14
7
20
7
20
7
14
0
7
14
14
0
7
% R
% Ser:
14
14
0
7
7
7
14
20
14
27
20
14
0
14
7
% S
% Thr:
14
14
27
0
0
0
14
0
7
7
7
14
14
0
27
% T
% Val:
0
7
7
0
7
0
14
7
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _