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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
41.21
Human Site:
S406
Identified Species:
64.76
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S406
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
S365
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
S365
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Dog
Lupus familis
XP_534385
583
65796
S388
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
S391
H
L
P
A
Q
S
G
S
S
R
V
L
D
A
M
Rat
Rattus norvegicus
Q9JLH6
586
65848
S389
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
S367
H
L
P
A
Q
S
G
S
T
R
V
L
E
A
M
Frog
Xenopus laevis
NP_001090499
565
63917
S372
H
I
P
A
Q
S
G
S
N
R
V
L
E
S
M
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
S383
H
L
P
V
Q
S
G
S
S
R
I
L
H
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
N385
H
L
P
A
Q
S
G
N
T
Q
V
L
E
R
M
Honey Bee
Apis mellifera
XP_393868
618
71037
N421
H
L
P
A
Q
S
G
N
S
R
I
L
E
K
M
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
D369
H
L
P
A
Q
S
G
D
D
E
T
L
E
R
M
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
T378
E
L
V
D
H
V
Q
T
A
I
P
G
V
A
L
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
S417
H
L
P
A
Q
T
G
S
S
T
V
L
E
R
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
N429
H
L
P
A
Q
S
G
N
S
R
I
L
E
Q
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
80
80
N.A.
73.3
80
66.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
93.3
93.3
66.6
33.3
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
80
N.A.
N.A.
80
N.A.
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
87
0
0
0
0
7
0
0
0
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
7
7
0
0
0
7
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
7
0
0
80
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
94
0
0
0
0
7
0
0
0
% G
% His:
94
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
7
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
94
0
0
0
0
0
0
0
0
0
94
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
94
% M
% Asn:
0
0
0
0
0
0
0
20
7
0
0
0
0
0
0
% N
% Pro:
0
0
94
0
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
94
0
7
0
0
7
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
74
0
0
0
20
0
% R
% Ser:
0
0
0
0
0
87
0
67
67
0
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
7
0
7
14
7
7
0
0
0
0
% T
% Val:
0
0
7
7
0
7
0
0
0
0
67
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _