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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
51.52
Human Site:
S459
Identified Species:
80.95
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S459
E
D
H
V
Q
T
V
S
L
L
R
E
V
Q
Y
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
S418
E
D
H
V
Q
T
V
S
L
L
R
E
V
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
S418
E
D
H
V
Q
T
V
S
L
L
R
E
V
Q
Y
Dog
Lupus familis
XP_534385
583
65796
S441
E
D
H
L
Q
T
V
S
L
L
R
E
V
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
S444
D
D
H
R
Q
T
V
S
L
L
R
E
V
Q
Y
Rat
Rattus norvegicus
Q9JLH6
586
65848
S442
D
D
H
L
Q
T
V
S
L
L
R
E
V
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
S420
E
D
H
Q
Q
T
V
S
L
L
R
E
V
R
Y
Frog
Xenopus laevis
NP_001090499
565
63917
S425
E
D
H
Q
Q
T
L
S
L
L
R
E
V
S
Y
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
S436
E
D
H
Q
Q
T
I
S
L
L
K
E
V
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
S438
E
E
F
Q
D
T
V
S
L
I
Q
Q
V
Q
Y
Honey Bee
Apis mellifera
XP_393868
618
71037
S474
E
E
F
Q
D
T
L
S
L
I
E
L
I
K
Y
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
S422
Q
A
H
Q
N
T
L
S
L
I
R
A
V
R
Y
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
H431
R
Q
K
T
H
A
Y
H
K
M
Q
D
D
V
P
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
S470
E
E
H
Q
D
T
L
S
L
V
K
A
V
G
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
S482
E
E
H
Q
E
T
L
S
L
V
R
A
V
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
73.3
N.A.
53.3
33.3
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
80
66.6
73.3
20
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
0
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
60
0
0
20
0
0
0
0
0
0
7
7
0
0
% D
% Glu:
74
27
0
0
7
0
0
0
0
0
7
60
0
0
0
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
80
0
7
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
20
0
0
7
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
7
0
14
0
0
7
0
% K
% Leu:
0
0
0
14
0
0
34
0
94
60
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
7
0
54
60
0
0
0
0
0
14
7
0
47
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
0
67
0
0
14
0
% R
% Ser:
0
0
0
0
0
0
0
94
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
7
0
94
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
20
0
0
54
0
0
14
0
0
87
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
94
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _