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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
0.3
Human Site:
S57
Identified Species:
0.48
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S57
G
A
R
K
D
F
S
S
R
L
A
A
G
P
T
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
E55
P
Q
E
K
L
S
S
E
V
E
D
P
P
P
Y
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
E55
P
Q
E
K
L
S
S
E
V
E
D
P
P
P
Y
Dog
Lupus familis
XP_534385
583
65796
F53
E
D
G
V
R
K
D
F
S
S
R
L
A
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
R56
A
Q
K
D
F
S
S
R
L
A
T
G
P
T
F
Rat
Rattus norvegicus
Q9JLH6
586
65848
R54
V
Q
K
D
F
S
S
R
L
A
T
G
P
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
L52
G
P
D
L
R
H
F
L
R
G
A
A
A
P
P
Frog
Xenopus laevis
NP_001090499
565
63917
K57
F
V
N
T
K
P
A
K
T
V
S
P
A
D
D
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
S68
F
I
M
S
S
D
K
S
D
F
D
G
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
F59
G
P
G
F
Q
D
F
F
A
V
K
P
A
S
R
Honey Bee
Apis mellifera
XP_393868
618
71037
L89
V
E
R
K
T
N
D
L
E
R
F
R
D
L
T
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
K52
F
I
K
E
S
T
K
K
Q
R
Q
K
A
I
I
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
E57
R
S
R
R
V
Y
F
E
T
Y
G
C
Q
M
N
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
G71
S
K
N
T
Q
G
P
G
L
H
H
F
V
A
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
I86
R
S
F
S
I
S
Q
I
A
S
S
G
K
F
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
20
20
0
N.A.
6.6
6.6
N.A.
N.A.
33.3
0
6.6
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
20
20
0
N.A.
13.3
13.3
N.A.
N.A.
33.3
20
6.6
N.A.
13.3
20
20
26.6
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
7
0
14
14
14
14
34
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
7
7
14
7
14
14
0
7
0
20
0
7
7
14
% D
% Glu:
7
7
14
7
0
0
0
20
7
14
0
0
0
7
7
% E
% Phe:
20
0
7
7
14
7
20
14
0
7
7
7
0
7
14
% F
% Gly:
20
0
14
0
0
7
0
7
0
7
7
27
7
0
7
% G
% His:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% H
% Ile:
0
14
0
0
7
0
0
7
0
0
0
0
0
7
7
% I
% Lys:
0
7
20
27
7
7
14
14
0
0
7
7
7
0
0
% K
% Leu:
0
0
0
7
14
0
0
14
20
7
0
7
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
14
0
0
7
0
0
0
0
0
0
0
0
7
% N
% Pro:
14
14
0
0
0
7
7
0
0
0
0
27
27
27
7
% P
% Gln:
0
27
0
0
14
0
7
0
7
0
7
0
7
0
7
% Q
% Arg:
14
0
20
7
14
0
0
14
14
14
7
7
0
0
7
% R
% Ser:
7
14
0
14
14
34
34
14
7
14
14
0
7
7
0
% S
% Thr:
0
0
0
14
7
7
0
0
14
0
14
0
0
20
14
% T
% Val:
14
7
0
7
7
0
0
0
14
14
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _