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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
1.82
Human Site:
S81
Identified Species:
2.86
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
S81
A
P
Q
E
K
L
S
S
E
V
E
D
P
P
P
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
T79
Q
R
K
V
Y
L
E
T
Y
G
C
Q
M
N
V
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
T79
Q
R
K
V
Y
L
E
T
Y
G
C
Q
M
N
V
Dog
Lupus familis
XP_534385
583
65796
P77
A
S
A
P
Q
E
K
P
D
M
E
D
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
P80
P
Q
E
K
P
S
S
P
E
V
E
D
P
P
P
Rat
Rattus norvegicus
Q9JLH6
586
65848
P78
P
Q
E
K
P
S
S
P
E
V
E
D
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
K76
G
S
T
S
G
L
G
K
V
Y
L
E
T
Y
G
Frog
Xenopus laevis
NP_001090499
565
63917
N81
L
Y
P
P
S
Q
N
N
K
I
Y
L
E
T
Y
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
V92
M
S
D
H
S
R
K
V
Y
F
E
T
Y
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
N83
D
T
S
V
P
Y
L
N
S
I
D
F
N
G
N
Honey Bee
Apis mellifera
XP_393868
618
71037
I113
L
S
K
T
E
I
P
I
D
P
I
R
V
P
N
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
G76
L
N
P
E
D
L
Q
G
N
G
R
T
V
C
Y
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
Q81
I
L
E
K
S
G
F
Q
K
V
E
D
I
S
H
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
Q95
S
A
S
A
S
Q
T
Q
P
Q
F
V
P
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
L110
N
A
Q
A
H
A
S
L
T
T
P
E
T
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
6.6
6.6
40
N.A.
53.3
53.3
N.A.
N.A.
6.6
0
6.6
N.A.
0
6.6
13.3
20
P-Site Similarity:
100
20
20
60
N.A.
66.6
66.6
N.A.
N.A.
13.3
26.6
6.6
N.A.
20
33.3
13.3
40
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
7
14
0
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
14
0
0
7
7
% C
% Asp:
7
0
7
0
7
0
0
0
14
0
7
34
0
0
0
% D
% Glu:
0
0
20
14
7
7
14
0
20
0
40
14
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
7
7
7
0
0
0
% F
% Gly:
7
0
0
0
7
7
7
7
0
20
0
0
0
14
7
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
0
7
0
7
0
14
7
0
7
0
7
% I
% Lys:
0
0
20
20
7
0
14
7
14
0
0
0
0
0
0
% K
% Leu:
20
7
0
0
0
34
7
7
0
0
7
7
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
14
0
0
% M
% Asn:
7
7
0
0
0
0
7
14
7
0
0
0
7
14
14
% N
% Pro:
14
7
14
14
20
0
7
20
7
7
7
0
34
34
27
% P
% Gln:
14
14
14
0
7
14
7
14
0
7
0
14
0
0
0
% Q
% Arg:
0
14
0
0
0
7
0
0
0
0
7
7
0
0
0
% R
% Ser:
7
27
14
7
27
14
27
7
7
0
0
0
0
7
7
% S
% Thr:
0
7
7
7
0
0
7
14
7
7
0
14
14
7
0
% T
% Val:
0
0
0
20
0
0
0
7
7
27
0
7
14
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
14
7
0
0
20
7
7
0
7
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _