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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
8.18
Human Site:
T167
Identified Species:
12.86
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
T167
H
Q
L
K
A
L
K
T
R
R
P
R
S
R
V
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
I165
A
E
R
L
K
E
E
I
L
N
R
E
K
M
V
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
I165
A
E
R
L
K
E
E
I
L
N
R
E
K
M
V
Dog
Lupus familis
XP_534385
583
65796
T163
Q
Q
L
K
A
L
K
T
K
R
L
R
S
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
T166
H
Q
L
K
V
L
K
T
K
R
P
R
S
R
V
Rat
Rattus norvegicus
Q9JLH6
586
65848
A164
H
Q
L
K
V
L
K
A
K
R
P
R
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
R162
I
L
G
C
M
A
E
R
L
K
E
E
I
L
H
Frog
Xenopus laevis
NP_001090499
565
63917
R167
I
L
G
C
M
A
E
R
L
K
Q
E
I
L
E
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
L178
L
G
C
M
A
E
R
L
K
S
E
L
L
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
Q169
S
T
R
R
H
P
L
Q
L
T
L
L
G
C
M
Honey Bee
Apis mellifera
XP_393868
618
71037
K199
T
D
L
N
H
L
R
K
K
K
K
K
N
P
I
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
V162
L
G
C
M
A
E
R
V
R
H
D
L
L
E
K
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
L167
Y
R
D
L
P
R
L
L
N
V
A
G
S
G
Q
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
K181
L
N
Y
F
W
F
L
K
R
H
W
K
S
N
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
K196
L
N
Y
F
W
F
L
K
R
E
W
K
V
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
6.6
6.6
80
N.A.
86.6
80
N.A.
N.A.
0
0
6.6
N.A.
0
13.3
13.3
6.6
P-Site Similarity:
100
20
20
86.6
N.A.
93.3
86.6
N.A.
N.A.
13.3
13.3
20
N.A.
13.3
53.3
20
20
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
27
14
0
7
0
0
7
0
0
0
7
% A
% Cys:
0
0
14
14
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
7
0
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
0
14
0
0
0
27
27
0
0
7
14
27
0
7
7
% E
% Phe:
0
0
0
14
0
14
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
14
0
0
0
0
0
0
0
0
7
7
7
0
% G
% His:
20
0
0
0
14
0
0
0
0
14
0
0
0
0
7
% H
% Ile:
14
0
0
0
0
0
0
14
0
0
0
0
14
0
7
% I
% Lys:
0
0
0
27
14
0
27
20
34
20
7
20
14
0
7
% K
% Leu:
27
14
34
20
0
34
27
14
34
0
14
20
14
14
0
% L
% Met:
0
0
0
14
14
0
0
0
0
0
0
0
0
14
7
% M
% Asn:
0
14
0
7
0
0
0
0
7
14
0
0
7
14
0
% N
% Pro:
0
0
0
0
7
7
0
0
0
0
20
0
0
7
0
% P
% Gln:
7
27
0
0
0
0
0
7
0
0
7
0
0
0
14
% Q
% Arg:
0
7
20
7
0
7
20
14
27
27
14
27
0
27
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
7
0
0
40
0
0
% S
% Thr:
7
7
0
0
0
0
0
20
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
14
0
0
7
0
7
0
0
7
0
47
% V
% Trp:
0
0
0
0
14
0
0
0
0
0
14
0
0
0
0
% W
% Tyr:
7
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _