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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
45.45
Human Site:
T270
Identified Species:
71.43
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
T270
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
E247
V
P
F
T
R
G
R
E
R
S
R
P
I
A
S
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
E247
V
P
F
T
R
G
R
E
R
S
R
P
V
A
S
Dog
Lupus familis
XP_534385
583
65796
T266
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
T269
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Rat
Rattus norvegicus
Q9JLH6
586
65848
T267
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
T245
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Frog
Xenopus laevis
NP_001090499
565
63917
T250
T
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
T260
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
T263
T
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Honey Bee
Apis mellifera
XP_393868
618
71037
G286
A
F
V
T
I
M
R
G
C
D
N
M
C
T
Y
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
T244
T
Y
C
V
V
P
F
T
R
G
R
E
R
S
R
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
V249
S
D
Q
G
V
K
E
V
T
V
L
G
Q
N
V
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
T293
S
F
C
I
V
P
F
T
R
G
R
E
R
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
T308
A
F
C
I
V
P
F
T
R
G
R
E
R
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
93.3
0
86.6
13.3
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
26.6
100
26.6
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
93.3
N.A.
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% A
% Cys:
0
0
74
0
0
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
14
0
0
0
74
0
0
0
% E
% Phe:
0
20
14
0
0
0
74
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
14
0
7
0
74
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
67
7
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
0
14
0
0
0
74
0
0
0
0
0
14
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
14
0
20
0
87
0
87
0
74
0
74
% R
% Ser:
54
0
0
0
0
0
0
0
0
14
0
0
0
74
14
% S
% Thr:
20
0
0
20
0
0
0
74
7
0
0
0
0
7
0
% T
% Val:
14
0
7
7
80
0
0
7
0
7
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _