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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK5RAP1 All Species: 0.91
Human Site: T64 Identified Species: 1.43
UniProt: Q96SZ6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SZ6 NP_057166.3 601 67689 T64 S R L A A G P T F Q H F L K S
Chimpanzee Pan troglodytes XP_001155512 560 62969 Y62 E V E D P P P Y L T M D E L L
Rhesus Macaque Macaca mulatta XP_001103977 560 62653 Y62 E V E D P P P Y L T M D E L L
Dog Lupus familis XP_534385 583 65796 G60 F S S R L A T G P T F Q H F L
Cat Felis silvestris
Mouse Mus musculus Q8BTW8 588 66091 F63 R L A T G P T F Q H F L R S A
Rat Rattus norvegicus Q9JLH6 586 65848 F61 R L A T G P T F Q H F L R S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417464 562 62266 P59 L R G A A A P P P A G E P E P
Frog Xenopus laevis NP_001090499 565 63917 D64 K T V S P A D D D D P P P Y I
Zebra Danio Brachydanio rerio NP_001103849 577 65835 E75 S D F D G S E E Y E E H Y I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGZ1 583 65810 R66 F A V K P A S R L K T D E E E
Honey Bee Apis mellifera XP_393868 618 71037 T96 L E R F R D L T R A G P S L K
Nematode Worm Caenorhab. elegans Q09316 547 61297 I59 K Q R Q K A I I P S I E D T K
Sea Urchin Strong. purpuratus XP_801957 561 63350 N64 E T Y G C Q M N V S D T E I A
Poplar Tree Populus trichocarpa XP_002310277 623 70342 Q78 G L H H F V A Q A A S S A S A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0V1 640 71703 D93 I A S S G K F D G P S L H Q F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.3 82.8 88.3 N.A. 85.8 84.3 N.A. N.A. 70.5 64.2 61 N.A. 51.2 50 47.4 53.7
Protein Similarity: 100 89 85.6 92.8 N.A. 91 89.5 N.A. N.A. 79.1 75.7 73.2 N.A. 67.3 68.4 64.2 69.2
P-Site Identity: 100 6.6 6.6 0 N.A. 0 0 N.A. N.A. 26.6 0 6.6 N.A. 0 6.6 0 0
P-Site Similarity: 100 6.6 6.6 0 N.A. 6.6 6.6 N.A. N.A. 33.3 13.3 20 N.A. 20 6.6 6.6 6.6
Percent
Protein Identity: 47.6 N.A. N.A. 45.6 N.A. N.A.
Protein Similarity: 64.6 N.A. N.A. 62.1 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 14 14 14 34 7 0 7 20 0 0 7 0 27 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 20 0 7 7 14 7 7 7 20 7 0 0 % D
% Glu: 20 7 14 0 0 0 7 7 0 7 7 14 27 14 7 % E
% Phe: 14 0 7 7 7 0 7 14 7 0 20 7 0 7 7 % F
% Gly: 7 0 7 7 27 7 0 7 7 0 14 0 0 0 0 % G
% His: 0 0 7 7 0 0 0 0 0 14 7 7 14 0 0 % H
% Ile: 7 0 0 0 0 0 7 7 0 0 7 0 0 14 7 % I
% Lys: 14 0 0 7 7 7 0 0 0 7 0 0 0 7 14 % K
% Leu: 14 20 7 0 7 0 7 0 20 0 0 20 7 20 20 % L
% Met: 0 0 0 0 0 0 7 0 0 0 14 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 27 27 27 7 20 7 7 14 14 0 14 % P
% Gln: 0 7 0 7 0 7 0 7 14 7 0 7 0 7 0 % Q
% Arg: 14 14 14 7 7 0 0 7 7 0 0 0 14 0 0 % R
% Ser: 14 7 14 14 0 7 7 0 0 14 14 7 7 20 7 % S
% Thr: 0 14 0 14 0 0 20 14 0 20 7 7 0 7 0 % T
% Val: 0 14 14 0 0 7 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 14 7 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _