KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
4.85
Human Site:
Y345
Identified Species:
7.62
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
Y345
S
R
G
F
T
T
N
Y
K
T
K
Q
G
G
L
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
H315
Q
G
G
L
R
F
A
H
L
L
D
Q
V
S
R
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
H315
Q
G
G
L
R
F
A
H
L
L
D
Q
V
S
R
Dog
Lupus familis
XP_534385
583
65796
L334
Y
K
P
K
K
G
G
L
R
F
T
Y
L
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
L337
Y
K
P
K
Q
G
G
L
R
F
S
H
L
L
D
Rat
Rattus norvegicus
Q9JLH6
586
65848
H339
Q
G
G
L
R
F
S
H
L
L
D
Q
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
L313
Y
K
T
K
P
G
G
L
R
F
A
H
L
L
D
Frog
Xenopus laevis
NP_001090499
565
63917
L318
Y
K
H
K
K
G
G
L
R
F
V
D
L
L
D
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
D333
Q
G
G
L
R
F
A
D
L
L
D
R
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
A335
T
G
G
T
P
F
A
A
L
L
R
S
V
A
Q
Honey Bee
Apis mellifera
XP_393868
618
71037
Y360
A
K
G
F
K
T
V
Y
K
N
K
K
G
G
R
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
T319
S
G
G
L
T
F
T
T
L
L
E
K
V
A
D
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
P322
M
R
I
R
F
T
S
P
H
P
K
D
F
P
D
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
D367
R
V
G
L
R
F
S
D
L
L
D
R
L
S
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
D379
N
M
G
L
R
F
A
D
L
L
D
R
L
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
13.3
13.3
0
N.A.
0
13.3
N.A.
N.A.
0
0
13.3
N.A.
6.6
53.3
20
20
P-Site Similarity:
100
20
20
13.3
N.A.
13.3
26.6
N.A.
N.A.
13.3
13.3
20
N.A.
20
73.3
33.3
26.6
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
34
7
0
0
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
40
14
0
0
40
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
14
7
54
0
0
0
27
0
0
7
0
0
% F
% Gly:
0
40
67
0
0
27
27
0
0
0
0
0
14
14
0
% G
% His:
0
0
7
0
0
0
0
20
7
0
0
14
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
34
0
27
20
0
0
0
14
0
20
14
0
0
0
% K
% Leu:
0
0
0
47
0
0
0
27
54
54
0
0
40
27
14
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
14
0
14
0
0
7
0
7
0
0
0
7
0
% P
% Gln:
27
0
0
0
7
0
0
0
0
0
0
27
0
0
7
% Q
% Arg:
7
14
0
7
40
0
0
0
27
0
7
20
0
0
27
% R
% Ser:
14
0
0
0
0
0
20
0
0
0
7
7
0
40
0
% S
% Thr:
7
0
7
7
14
20
7
7
0
7
7
0
0
0
7
% T
% Val:
0
7
0
0
0
0
7
0
0
0
7
0
40
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
27
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _