KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP1
All Species:
52.12
Human Site:
Y422
Identified Species:
81.9
UniProt:
Q96SZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SZ6
NP_057166.3
601
67689
Y422
R
G
Y
S
R
E
A
Y
V
E
L
V
H
H
I
Chimpanzee
Pan troglodytes
XP_001155512
560
62969
Y381
R
G
Y
S
R
E
A
Y
V
E
L
V
H
H
I
Rhesus Macaque
Macaca mulatta
XP_001103977
560
62653
S381
R
G
Y
C
V
P
V
S
I
Y
L
T
C
H
P
Dog
Lupus familis
XP_534385
583
65796
Y404
R
G
Y
S
R
E
A
Y
V
E
L
I
H
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW8
588
66091
Y407
R
G
Y
S
R
E
A
Y
V
A
L
V
H
H
V
Rat
Rattus norvegicus
Q9JLH6
586
65848
Y405
R
G
Y
S
R
E
A
Y
V
A
L
V
H
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417464
562
62266
Y383
R
G
Y
T
R
E
A
Y
L
E
L
V
Q
H
V
Frog
Xenopus laevis
NP_001090499
565
63917
Y388
R
G
Y
S
R
E
A
Y
L
D
L
I
Q
N
I
Zebra Danio
Brachydanio rerio
NP_001103849
577
65835
Y399
R
G
Y
T
R
E
A
Y
L
E
L
V
E
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGZ1
583
65810
Y401
R
G
Y
S
R
E
A
Y
L
E
L
V
Q
H
I
Honey Bee
Apis mellifera
XP_393868
618
71037
Y437
R
G
Y
T
R
E
A
Y
I
D
L
V
H
H
I
Nematode Worm
Caenorhab. elegans
Q09316
547
61297
Y385
R
G
Y
T
R
D
L
Y
L
R
L
V
D
D
I
Sea Urchin
Strong. purpuratus
XP_801957
561
63350
C394
S
D
F
I
A
G
F
C
G
E
T
E
E
D
H
Poplar Tree
Populus trichocarpa
XP_002310277
623
70342
Y433
R
G
Y
T
R
E
A
Y
L
D
L
V
Q
K
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0V1
640
71703
Y445
R
G
Y
T
R
E
A
Y
L
D
L
V
K
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
82.8
88.3
N.A.
85.8
84.3
N.A.
N.A.
70.5
64.2
61
N.A.
51.2
50
47.4
53.7
Protein Similarity:
100
89
85.6
92.8
N.A.
91
89.5
N.A.
N.A.
79.1
75.7
73.2
N.A.
67.3
68.4
64.2
69.2
P-Site Identity:
100
100
33.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
73.3
66.6
73.3
N.A.
86.6
80
53.3
6.6
P-Site Similarity:
100
100
40
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
93.3
100
73.3
13.3
Percent
Protein Identity:
47.6
N.A.
N.A.
45.6
N.A.
N.A.
Protein Similarity:
64.6
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
80
0
0
14
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
7
0
0
0
0
7
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
27
0
0
7
14
0
% D
% Glu:
0
0
0
0
0
80
0
0
0
47
0
7
14
0
0
% E
% Phe:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
94
0
0
0
7
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
40
60
7
% H
% Ile:
0
0
0
7
0
0
0
0
14
0
0
14
0
0
74
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
0
% K
% Leu:
0
0
0
0
0
0
7
0
47
0
94
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
27
0
0
% Q
% Arg:
94
0
0
0
87
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
0
47
0
0
0
7
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
40
0
0
0
0
0
0
7
7
0
0
0
% T
% Val:
0
0
0
0
7
0
7
0
34
0
0
74
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
94
0
0
0
0
87
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _