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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZIC5
All Species:
16.06
Human Site:
S621
Identified Species:
44.17
UniProt:
Q96T25
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T25
NP_149123.2
639
65849
S621
P
S
S
N
G
T
T
S
E
T
E
D
E
E
I
Chimpanzee
Pan troglodytes
XP_522708
518
56500
S500
P
S
S
N
G
T
T
S
E
T
E
D
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001093521
362
38822
E345
S
S
N
G
T
T
S
E
S
E
D
E
E
I
Y
Dog
Lupus familis
XP_854266
644
66365
S626
P
S
S
N
G
T
T
S
E
S
E
D
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61467
341
37418
P324
S
L
E
S
G
R
E
P
S
V
A
C
S
A
A
Rat
Rattus norvegicus
NP_001101861
265
29465
E248
S
S
N
G
T
T
S
E
S
E
D
E
E
M
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521150
329
36173
E312
S
S
N
G
T
T
S
E
S
E
D
E
E
I
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9IB89
515
56428
S498
A
S
S
N
A
D
S
S
E
S
E
D
D
E
E
Zebra Danio
Brachydanio rerio
NP_991290
497
54584
S480
P
S
S
D
V
P
T
S
E
S
D
D
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
55.4
93.3
N.A.
37
38.9
N.A.
40
N.A.
52.2
53.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.7
55.8
94.5
N.A.
43.8
39.9
N.A.
45.3
N.A.
59.3
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
6.6
20
N.A.
20
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
13.3
46.6
N.A.
46.6
N.A.
73.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
12
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
12
0
12
0
0
0
0
45
56
12
12
0
% D
% Glu:
0
0
12
0
0
0
12
34
56
34
45
34
78
45
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
34
45
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
34
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
34
45
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
45
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
45
89
56
12
0
0
45
56
45
34
0
0
12
0
12
% S
% Thr:
0
0
0
0
34
67
45
0
0
23
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _