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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK17
All Species:
10.3
Human Site:
S54
Identified Species:
25.19
UniProt:
Q96T54
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T54
NP_001128583.1
332
36895
S54
A
A
Q
D
S
S
R
S
F
Q
R
D
K
W
E
Chimpanzee
Pan troglodytes
XP_001173849
332
36762
S54
A
A
Q
D
S
S
R
S
F
Q
R
D
K
W
E
Rhesus Macaque
Macaca mulatta
XP_001117122
332
37036
S54
A
A
Q
E
S
S
R
S
F
Q
R
D
K
W
E
Dog
Lupus familis
XP_538902
294
32552
R44
K
Q
A
E
A
Q
S
R
D
Q
F
Q
F
E
K
Cat
Felis silvestris
Mouse
Mus musculus
O88454
398
43033
L58
P
C
V
S
Q
K
S
L
E
D
F
I
K
L
L
Rat
Rattus norvegicus
Q9JIS4
538
59782
I105
E
S
S
Q
K
N
T
I
A
L
E
K
A
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507173
404
44807
L61
F
L
E
N
Y
T
C
L
D
R
Q
A
L
E
Q
Chicken
Gallus gallus
XP_419477
380
41713
R107
A
E
V
R
A
A
R
R
L
L
Q
Q
R
W
E
Frog
Xenopus laevis
Q63ZI0
374
42700
G50
A
E
E
I
R
L
K
G
K
Y
N
I
S
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
T50
R
V
R
E
K
L
K
T
K
Y
N
M
S
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.4
41.5
N.A.
31.4
23.2
N.A.
34.6
45.2
25.1
N.A.
N.A.
N.A.
N.A.
26.2
N.A.
Protein Similarity:
100
98.8
95.4
57.8
N.A.
46.4
37.9
N.A.
51.2
56.3
43.5
N.A.
N.A.
N.A.
N.A.
43.6
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
0
26.6
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
6.6
13.3
N.A.
40
53.3
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
30
10
0
20
10
0
0
10
0
0
10
10
0
10
% A
% Cys:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
20
10
0
30
0
0
0
% D
% Glu:
10
20
20
30
0
0
0
0
10
0
10
0
0
30
50
% E
% Phe:
10
0
0
0
0
0
0
0
30
0
20
0
10
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
20
0
0
0
% I
% Lys:
10
0
0
0
20
10
20
0
20
0
0
10
40
0
10
% K
% Leu:
0
10
0
0
0
20
0
20
10
20
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
20
0
0
10
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
30
10
10
10
0
0
0
40
20
20
0
0
10
% Q
% Arg:
10
0
10
10
10
0
40
20
0
10
30
0
10
0
0
% R
% Ser:
0
10
10
10
30
30
20
30
0
0
0
0
20
10
0
% S
% Thr:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% T
% Val:
0
10
20
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _