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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK16
All Species:
32.73
Human Site:
Y218
Identified Species:
65.45
UniProt:
Q96T55
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T55
NP_001128578.1
309
34153
Y218
S
T
I
G
F
G
D
Y
V
V
G
T
D
P
S
Chimpanzee
Pan troglodytes
XP_001173879
309
34164
Y218
S
T
I
G
F
G
D
Y
V
V
G
T
D
P
S
Rhesus Macaque
Macaca mulatta
XP_001117141
309
34306
Y218
S
T
I
G
F
G
D
Y
V
V
G
T
D
P
S
Dog
Lupus familis
XP_538902
294
32552
Y218
S
T
I
G
F
G
D
Y
V
V
G
T
D
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P97438
411
45279
Y257
T
T
I
G
F
G
D
Y
V
A
G
G
S
D
I
Rat
Rattus norvegicus
Q9JIS4
538
59782
F282
T
T
V
G
F
G
D
F
V
A
G
G
N
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507173
404
44807
Y218
S
T
I
G
F
G
D
Y
V
V
G
T
D
P
N
Chicken
Gallus gallus
XP_001235224
294
33443
Y218
S
T
I
G
F
G
D
Y
V
V
G
A
N
P
N
Frog
Xenopus laevis
Q63ZI0
374
42700
S270
S
L
A
G
N
R
N
S
M
I
I
H
I
Q
E
Zebra Danio
Brachydanio rerio
NP_001154871
551
61477
Y285
T
T
I
G
I
G
D
Y
V
A
G
G
D
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
Y204
T
T
I
G
F
G
D
Y
V
A
L
Q
K
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL25
443
49308
R319
T
T
V
G
Y
G
D
R
A
F
N
T
L
A
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
83.1
N.A.
29.2
24.3
N.A.
54.4
59.2
26.4
25.4
N.A.
N.A.
N.A.
29.4
N.A.
Protein Similarity:
100
99.6
97.4
86.7
N.A.
46.4
38.4
N.A.
62.3
72.1
42.2
36.1
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
60
46.6
N.A.
93.3
80
13.3
60
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
66.6
73.3
N.A.
100
93.3
33.3
66.6
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
34
0
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
92
0
0
0
0
0
50
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
75
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
100
0
92
0
0
0
0
75
25
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
75
0
9
0
0
0
0
9
9
0
9
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
0
9
0
17
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
9
0
9
0
0
0
0
0
17
0
% R
% Ser:
59
0
0
0
0
0
0
9
0
0
0
0
9
0
34
% S
% Thr:
42
92
0
0
0
0
0
0
0
0
0
50
0
0
0
% T
% Val:
0
0
17
0
0
0
0
0
84
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _