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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK16
All Species:
26.36
Human Site:
Y228
Identified Species:
52.73
UniProt:
Q96T55
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T55
NP_001128578.1
309
34153
Y228
G
T
D
P
S
K
H
Y
I
S
V
Y
R
S
L
Chimpanzee
Pan troglodytes
XP_001173879
309
34164
Y228
G
T
D
P
S
K
H
Y
I
S
V
Y
R
S
L
Rhesus Macaque
Macaca mulatta
XP_001117141
309
34306
Y228
G
T
D
P
S
K
H
Y
I
S
V
Y
R
S
L
Dog
Lupus familis
XP_538902
294
32552
Y228
G
T
D
P
S
K
H
Y
I
S
V
Y
R
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P97438
411
45279
L267
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
V
Rat
Rattus norvegicus
Q9JIS4
538
59782
Y292
G
G
N
A
G
I
N
Y
R
E
W
Y
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507173
404
44807
Y228
G
T
D
P
N
K
H
Y
I
S
V
Y
R
S
L
Chicken
Gallus gallus
XP_001235224
294
33443
Y228
G
A
N
P
N
K
H
Y
I
P
L
Y
R
S
L
Frog
Xenopus laevis
Q63ZI0
374
42700
P280
I
H
I
Q
E
D
T
P
H
G
R
Q
R
Y
K
Zebra Danio
Brachydanio rerio
NP_001154871
551
61477
Y295
G
G
D
R
K
I
E
Y
M
K
W
Y
K
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
Q214
L
Q
K
R
G
S
L
Q
T
Q
P
E
Y
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL25
443
49308
L329
N
T
L
A
G
R
L
L
A
A
M
W
L
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
83.1
N.A.
29.2
24.3
N.A.
54.4
59.2
26.4
25.4
N.A.
N.A.
N.A.
29.4
N.A.
Protein Similarity:
100
99.6
97.4
86.7
N.A.
46.4
38.4
N.A.
62.3
72.1
42.2
36.1
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
26.6
N.A.
93.3
66.6
6.6
33.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
46.6
N.A.
100
86.6
6.6
46.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
0
0
9
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
9
0
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
9
9
0
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
75
25
0
0
25
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
50
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
9
17
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
9
50
0
0
0
9
0
9
17
0
9
% K
% Leu:
9
0
9
0
0
0
17
17
0
0
9
0
9
9
67
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
9
0
17
0
17
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
0
0
0
9
0
9
9
0
9
17
0
% P
% Gln:
0
9
0
9
0
0
0
9
0
9
0
9
0
0
0
% Q
% Arg:
0
0
0
17
0
9
0
0
9
0
9
0
59
0
0
% R
% Ser:
0
0
9
0
34
9
0
0
0
42
0
0
0
50
0
% S
% Thr:
0
50
0
0
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
42
0
0
17
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
67
0
0
9
67
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _