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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMNAT3
All Species:
26.06
Human Site:
S179
Identified Species:
44.1
UniProt:
Q96T66
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T66
NP_835471.1
252
28322
S179
P
K
G
Y
I
A
E
S
P
I
L
R
M
H
Q
Chimpanzee
Pan troglodytes
XP_001158899
252
28306
S179
P
K
G
Y
I
A
E
S
P
I
L
R
M
H
Q
Rhesus Macaque
Macaca mulatta
XP_001113442
252
28225
S179
P
K
G
Y
I
S
E
S
P
I
L
R
M
H
Q
Dog
Lupus familis
XP_534286
297
33170
S212
P
K
E
Y
I
S
G
S
P
I
L
H
R
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99JR6
245
27684
S178
P
E
R
Y
I
S
D
S
P
I
L
Q
Q
F
Q
Rat
Rattus norvegicus
Q0HA29
307
34426
D238
P
R
D
A
A
D
A
D
R
I
M
N
H
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505547
211
24110
D146
C
V
N
R
P
G
C
D
P
L
Q
Y
I
S
E
Chicken
Gallus gallus
XP_422634
388
44256
S303
P
A
Q
Y
I
N
E
S
E
L
L
T
K
C
Q
Frog
Xenopus laevis
NP_001091188
278
32072
S199
A
S
N
F
I
Y
E
S
D
I
L
W
K
Y
K
Zebra Danio
Brachydanio rerio
Q6PC93
304
34191
E235
P
R
D
G
A
D
T
E
R
I
M
N
H
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651315
389
43777
S228
P
G
K
F
I
F
D
S
D
I
L
T
K
Y
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91851
223
25149
P158
L
S
R
E
G
S
N
P
L
N
T
I
Q
S
M
Sea Urchin
Strong. purpuratus
XP_783084
287
32645
S222
P
Y
K
F
I
Y
E
S
D
L
L
F
K
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06178
401
45841
H332
V
R
S
F
L
L
S
H
D
I
M
Y
E
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.8
67.6
N.A.
80.5
31.6
N.A.
55.1
41.7
47.4
30.2
N.A.
33.4
N.A.
36.1
44.6
Protein Similarity:
100
99.5
96.8
75
N.A.
87.6
47.8
N.A.
65
52
63.3
47.3
N.A.
44.2
N.A.
50.7
60.9
P-Site Identity:
100
100
93.3
53.3
N.A.
53.3
13.3
N.A.
6.6
46.6
33.3
13.3
N.A.
40
N.A.
0
33.3
P-Site Similarity:
100
100
100
73.3
N.A.
80
26.6
N.A.
26.6
53.3
53.3
26.6
N.A.
60
N.A.
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
15
15
8
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
15
0
0
15
15
15
29
0
0
0
0
0
0
% D
% Glu:
0
8
8
8
0
0
43
8
8
0
0
0
8
0
8
% E
% Phe:
0
0
0
29
0
8
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
8
22
8
8
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
15
29
0
% H
% Ile:
0
0
0
0
65
0
0
0
0
72
0
8
8
0
0
% I
% Lys:
0
29
15
0
0
0
0
0
0
0
0
0
29
0
8
% K
% Leu:
8
0
0
0
8
8
0
0
8
22
65
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
22
0
22
0
8
% M
% Asn:
0
0
15
0
0
8
8
0
0
8
0
15
0
0
0
% N
% Pro:
72
0
0
0
8
0
0
8
43
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
8
15
0
43
% Q
% Arg:
0
22
15
8
0
0
0
0
15
0
0
22
8
0
15
% R
% Ser:
0
15
8
0
0
29
8
65
0
0
0
0
0
29
22
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
15
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
43
0
15
0
0
0
0
0
15
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _