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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMNAT3
All Species:
8.44
Human Site:
S246
Identified Species:
14.29
UniProt:
Q96T66
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T66
NP_835471.1
252
28322
S246
W
K
G
K
S
T
Q
S
T
E
G
K
T
S
_
Chimpanzee
Pan troglodytes
XP_001158899
252
28306
S246
W
K
G
K
S
T
Q
S
T
E
G
K
T
C
_
Rhesus Macaque
Macaca mulatta
XP_001113442
252
28225
S246
W
K
G
K
S
T
Q
S
A
E
G
K
T
S
_
Dog
Lupus familis
XP_534286
297
33170
R279
R
K
G
S
S
T
Q
R
N
E
G
K
P
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99JR6
245
27684
Rat
Rattus norvegicus
Q0HA29
307
34426
K298
P
V
I
D
Y
I
L
K
S
Q
L
Y
I
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505547
211
24110
Chicken
Gallus gallus
XP_422634
388
44256
L370
R
K
N
E
G
D
L
L
Q
P
L
K
L
H
N
Frog
Xenopus laevis
NP_001091188
278
32072
L266
E
K
N
S
G
V
I
L
E
P
L
A
R
N
T
Zebra Danio
Brachydanio rerio
Q6PC93
304
34191
Q295
P
V
I
D
Y
I
L
Q
S
Q
L
Y
I
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651315
389
43777
P295
Y
I
T
D
A
V
R
P
N
H
L
L
F
N
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91851
223
25149
Sea Urchin
Strong. purpuratus
XP_783084
287
32645
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06178
401
45841
Q395
D
Q
T
E
P
V
K
Q
V
L
G
N
K
E
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.8
67.6
N.A.
80.5
31.6
N.A.
55.1
41.7
47.4
30.2
N.A.
33.4
N.A.
36.1
44.6
Protein Similarity:
100
99.5
96.8
75
N.A.
87.6
47.8
N.A.
65
52
63.3
47.3
N.A.
44.2
N.A.
50.7
60.9
P-Site Identity:
100
92.8
92.8
60
N.A.
0
0
N.A.
0
13.3
6.6
0
N.A.
0
N.A.
0
0
P-Site Similarity:
100
92.8
92.8
60
N.A.
0
20
N.A.
0
20
13.3
20
N.A.
26.6
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
7.1
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
28.5
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
22
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
15
0
0
0
0
8
29
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
29
0
15
0
0
0
0
0
36
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% H
% Ile:
0
8
15
0
0
15
8
0
0
0
0
0
15
0
0
% I
% Lys:
0
43
0
22
0
0
8
8
0
0
0
36
8
0
0
% K
% Leu:
0
0
0
0
0
0
22
15
0
8
36
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
15
0
0
8
0
29
8
% N
% Pro:
15
0
0
0
8
0
0
8
0
15
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
0
29
15
8
15
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
15
29
0
0
22
15
0
0
0
0
22
0
% S
% Thr:
0
0
15
0
0
29
0
0
15
0
0
0
22
0
8
% T
% Val:
0
15
0
0
0
22
0
0
8
0
0
0
0
0
0
% V
% Trp:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
15
0
0
0
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% _