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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETDB2
All Species:
7.88
Human Site:
Y208
Identified Species:
57.78
UniProt:
Q96T68
Number Species:
3
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T68
NP_001153780.1
719
81894
Y208
N
V
E
E
V
F
R
Y
L
L
E
T
E
C
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8C267
713
80618
Y212
N
M
E
E
V
F
H
Y
L
L
E
T
E
C
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6YI93
699
78253
I208
S
P
D
D
L
S
H
I
L
Y
K
A
P
C
G
Zebra Danio
Brachydanio rerio
Q08BR4
1216
135792
Y645
N
M
T
E
I
Q
R
Y
L
F
Q
T
Q
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
N.A.
N.A.
N.A.
35.8
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
78.5
N.A.
N.A.
N.A.
N.A.
51.4
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
46.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% C
% Asp:
0
0
25
25
0
0
0
0
0
0
0
0
0
0
25
% D
% Glu:
0
0
50
75
0
0
0
0
0
0
50
0
50
0
0
% E
% Phe:
0
0
0
0
0
50
0
0
0
25
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
25
0
0
25
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% K
% Leu:
0
0
0
0
25
0
0
0
100
50
0
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
25
0
0
0
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
25
0
0
0
0
25
0
25
0
0
% Q
% Arg:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% R
% Ser:
25
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
25
0
0
0
0
0
0
0
0
75
0
0
0
% T
% Val:
0
25
0
0
50
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _