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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETDB2 All Species: 7.88
Human Site: Y208 Identified Species: 57.78
UniProt: Q96T68 Number Species: 3
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T68 NP_001153780.1 719 81894 Y208 N V E E V F R Y L L E T E C N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8C267 713 80618 Y212 N M E E V F H Y L L E T E C N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6YI93 699 78253 I208 S P D D L S H I L Y K A P C G
Zebra Danio Brachydanio rerio Q08BR4 1216 135792 Y645 N M T E I Q R Y L F Q T Q C D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 67.1 N.A. N.A. N.A. N.A. 35.8 23.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. 78.5 N.A. N.A. N.A. N.A. 51.4 37.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. 86.6 N.A. N.A. N.A. N.A. 13.3 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 93.3 N.A. N.A. N.A. N.A. 46.6 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % C
% Asp: 0 0 25 25 0 0 0 0 0 0 0 0 0 0 25 % D
% Glu: 0 0 50 75 0 0 0 0 0 0 50 0 50 0 0 % E
% Phe: 0 0 0 0 0 50 0 0 0 25 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % G
% His: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 25 0 0 25 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % K
% Leu: 0 0 0 0 25 0 0 0 100 50 0 0 0 0 0 % L
% Met: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % N
% Pro: 0 25 0 0 0 0 0 0 0 0 0 0 25 0 0 % P
% Gln: 0 0 0 0 0 25 0 0 0 0 25 0 25 0 0 % Q
% Arg: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % R
% Ser: 25 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 25 0 0 0 0 0 0 0 0 75 0 0 0 % T
% Val: 0 25 0 0 50 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 25 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _