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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMS19 All Species: 26.06
Human Site: S273 Identified Species: 63.7
UniProt: Q96T76 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T76 NP_071757.4 1030 113290 S273 K V D S E V L S A K L D S L Q
Chimpanzee Pan troglodytes XP_001163153 1030 113188 S273 K V D S E V L S A K L D S L Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534982 1029 113066 S273 K V D S E I L S A K L D S L Q
Cat Felis silvestris
Mouse Mus musculus Q9D071 1031 113070 S274 K V D S E I L S A K L D S L Q
Rat Rattus norvegicus Q5I0I8 516 58844
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421710 1017 112552 S260 K M D S D L Q S A K L D S L Q
Frog Xenopus laevis NP_001087156 1022 113029 S265 K M D S E M Q S A K L D S L Q
Zebra Danio Brachydanio rerio XP_001920456 1016 110604 S265 K M D S D V Q S A K V D S M H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791246 974 107598 D225 D L Q T A R L D S Y Q L L Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40469 1032 117864 V275 K L T A S S P V V K N D T L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 93.1 N.A. 89.9 20.1 N.A. N.A. 71.5 65 55.1 N.A. N.A. N.A. N.A. 33
Protein Similarity: 100 99.7 N.A. 96.3 N.A. 94 31.9 N.A. N.A. 83.1 80.2 71.8 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 0 N.A. N.A. 73.3 80 60 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 0 N.A. N.A. 93.3 93.3 86.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 70 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 70 0 20 0 0 10 0 0 0 80 0 0 0 % D
% Glu: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % I
% Lys: 80 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % K
% Leu: 0 20 0 0 0 10 50 0 0 0 60 10 10 70 10 % L
% Met: 0 30 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 30 0 0 0 10 0 0 10 60 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 70 10 10 0 70 10 0 0 0 70 0 0 % S
% Thr: 0 0 10 10 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 40 0 0 0 30 0 10 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _