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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMS19 All Species: 14.24
Human Site: S41 Identified Species: 34.81
UniProt: Q96T76 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T76 NP_071757.4 1030 113290 S41 Q V A A D V K S G N Y T V L Q
Chimpanzee Pan troglodytes XP_001163153 1030 113188 S41 Q V A A D V K S G N Y T V L Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534982 1029 113066 S41 Q V A A D V K S G S Y T V L Q
Cat Felis silvestris
Mouse Mus musculus Q9D071 1031 113070 S42 Q V A A D V K S G G Y T V L Q
Rat Rattus norvegicus Q5I0I8 516 58844
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421710 1017 112552 D28 G L G R R L K D G S W T I L Q
Frog Xenopus laevis NP_001087156 1022 113029 D33 E V A A G V K D G V F T V L Q
Zebra Danio Brachydanio rerio XP_001920456 1016 110604 N33 D T S T G V K N G Q F T V L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791246 974 107598 T8 M G T Y L M S T E T R I R A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40469 1032 117864 H37 T V T D S I V H R S I K L L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 93.1 N.A. 89.9 20.1 N.A. N.A. 71.5 65 55.1 N.A. N.A. N.A. N.A. 33
Protein Similarity: 100 99.7 N.A. 96.3 N.A. 94 31.9 N.A. N.A. 83.1 80.2 71.8 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 0 N.A. N.A. 33.3 66.6 46.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 0 N.A. N.A. 66.6 80 66.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 50 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 40 0 0 20 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % F
% Gly: 10 10 10 0 20 0 0 0 70 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 10 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 70 0 0 0 0 10 0 0 10 % K
% Leu: 0 10 0 0 10 10 0 0 0 0 0 0 10 80 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 20 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 40 0 0 0 0 0 0 0 0 10 0 0 0 0 70 % Q
% Arg: 0 0 0 10 10 0 0 0 10 0 10 0 10 0 0 % R
% Ser: 0 0 10 0 10 0 10 40 0 30 0 0 0 0 0 % S
% Thr: 10 10 20 10 0 0 0 10 0 10 0 70 0 0 0 % T
% Val: 0 60 0 0 0 60 10 0 0 10 0 0 60 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 40 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _