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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSM2 All Species: 10.3
Human Site: S423 Identified Species: 32.38
UniProt: Q96T92 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T92 NP_115983.3 566 59491 S423 S T S G G R G S E I F V C P Y
Chimpanzee Pan troglodytes XP_522825 568 59533 S425 S T S G G R G S E I F V C P Y
Rhesus Macaque Macaca mulatta XP_001088093 568 59794 S425 S T S G G G G S E I F V C P Y
Dog Lupus familis XP_547774 557 58111 P414 S A S G V G G P E V F M C P Y
Cat Felis silvestris
Mouse Mus musculus Q9JMC2 493 52193 T375 Y L R K H L G T H E T G S A R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505849 397 42525 R279 H H C G K K F R R Q A Y L R K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001332514 508 57367 S389 V Y D C H Y C S K K F R R Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198951 484 53797 R366 R R P A N L R R H M Q Q H G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.7 84.4 N.A. 66.4 N.A. N.A. 35.8 N.A. N.A. 44.7 N.A. N.A. N.A. N.A. 28
Protein Similarity: 100 98.9 95.9 87.4 N.A. 71.7 N.A. N.A. 44.3 N.A. N.A. 55.6 N.A. N.A. N.A. N.A. 41.3
P-Site Identity: 100 100 93.3 60 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 73.3 N.A. 13.3 N.A. N.A. 13.3 N.A. N.A. 20 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 13 0 0 0 0 0 0 13 0 0 13 13 % A
% Cys: 0 0 13 13 0 0 13 0 0 0 0 0 50 0 0 % C
% Asp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 50 13 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 13 0 0 0 63 0 0 0 0 % F
% Gly: 0 0 0 63 38 25 63 0 0 0 0 13 0 13 0 % G
% His: 13 13 0 0 25 0 0 0 25 0 0 0 13 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 % I
% Lys: 0 0 0 13 13 13 0 0 13 13 0 0 0 0 13 % K
% Leu: 0 13 0 0 0 25 0 0 0 0 0 0 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 13 0 0 0 % M
% Asn: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 13 0 0 0 0 13 0 0 0 0 0 50 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 13 13 0 13 0 % Q
% Arg: 13 13 13 0 0 25 13 25 13 0 0 13 13 13 13 % R
% Ser: 50 0 50 0 0 0 0 50 0 0 0 0 13 0 0 % S
% Thr: 0 38 0 0 0 0 0 13 0 0 13 0 0 0 0 % T
% Val: 13 0 0 0 13 0 0 0 0 13 0 38 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 13 0 0 0 13 0 0 0 0 0 13 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _