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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSM2 All Species: 13.33
Human Site: Y440 Identified Species: 41.9
UniProt: Q96T92 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T92 NP_115983.3 566 59491 Y440 K K F R R Q A Y L R K H L S T
Chimpanzee Pan troglodytes XP_522825 568 59533 Y442 K K F R R Q A Y L R K H L S T
Rhesus Macaque Macaca mulatta XP_001088093 568 59794 Y442 K K F R R Q A Y L R K H L S T
Dog Lupus familis XP_547774 557 58111 Y431 K K F R R Q A Y L R K H L G T
Cat Felis silvestris
Mouse Mus musculus Q9JMC2 493 52193 R392 T P G F G S E R T A P L T F A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505849 397 42525 Q296 L A H H Q A L Q G K D R P G P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001332514 508 57367 E406 R K H L A A H E T I K A S S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198951 484 53797 G383 T F P C Q Y C G R V F N S L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.7 84.4 N.A. 66.4 N.A. N.A. 35.8 N.A. N.A. 44.7 N.A. N.A. N.A. N.A. 28
Protein Similarity: 100 98.9 95.9 87.4 N.A. 71.7 N.A. N.A. 44.3 N.A. N.A. 55.6 N.A. N.A. N.A. N.A. 41.3
P-Site Identity: 100 100 100 93.3 N.A. 0 N.A. N.A. 0 N.A. N.A. 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 0 N.A. N.A. 13.3 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 13 25 50 0 0 13 0 13 0 0 13 % A
% Cys: 0 0 0 13 0 0 13 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 13 13 0 0 0 0 0 0 0 % E
% Phe: 0 13 50 13 0 0 0 0 0 0 13 0 0 13 0 % F
% Gly: 0 0 13 0 13 0 0 13 13 0 0 0 0 25 0 % G
% His: 0 0 25 13 0 0 13 0 0 0 0 50 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % I
% Lys: 50 63 0 0 0 0 0 0 0 13 63 0 0 0 0 % K
% Leu: 13 0 0 13 0 0 13 0 50 0 0 13 50 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % N
% Pro: 0 13 13 0 0 0 0 0 0 0 13 0 13 0 13 % P
% Gln: 0 0 0 0 25 50 0 13 0 0 0 0 0 0 0 % Q
% Arg: 13 0 0 50 50 0 0 13 13 50 0 13 0 0 0 % R
% Ser: 0 0 0 0 0 13 0 0 0 0 0 0 25 50 0 % S
% Thr: 25 0 0 0 0 0 0 0 25 0 0 0 13 0 63 % T
% Val: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 50 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _