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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YME1L1
All Species:
15.15
Human Site:
S250
Identified Species:
23.81
UniProt:
Q96TA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96TA2
NP_055078.1
773
86455
S250
D
R
G
S
D
V
E
S
L
D
K
L
M
K
T
Chimpanzee
Pan troglodytes
XP_507710
903
100485
S380
D
R
G
S
D
V
E
S
L
D
K
L
M
K
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535172
804
89574
S281
D
R
G
S
D
V
E
S
L
D
K
L
M
K
T
Cat
Felis silvestris
Mouse
Mus musculus
O88967
715
80009
F240
R
R
T
R
L
I
L
F
V
L
L
L
F
G
I
Rat
Rattus norvegicus
Q925S8
715
79848
F240
R
R
T
R
L
I
L
F
V
L
L
L
F
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506440
766
85825
S243
D
R
G
S
D
V
E
S
L
D
K
L
M
K
T
Chicken
Gallus gallus
NP_001026683
722
81118
V243
L
L
S
F
F
L
F
V
L
C
F
Y
L
A
I
Frog
Xenopus laevis
NP_001084592
716
79844
L240
L
R
R
T
R
L
F
L
L
V
L
L
L
I
G
Zebra Danio
Brachydanio rerio
NP_001082983
722
79976
R240
Q
R
T
Q
E
S
L
R
R
T
R
L
I
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726263
736
80633
S242
G
Y
L
A
A
A
N
S
E
D
S
P
K
S
G
Honey Bee
Apis mellifera
XP_392703
709
79559
G243
G
L
R
F
S
M
D
G
I
K
F
R
P
E
T
Nematode Worm
Caenorhab. elegans
P54813
676
74435
E212
L
M
D
E
A
K
L
E
V
E
E
I
V
D
Y
Sea Urchin
Strong. purpuratus
XP_787399
733
80618
T240
Y
M
L
G
K
D
E
T
K
K
S
D
R
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80983
717
77256
E241
E
A
K
A
E
L
E
E
I
V
H
Y
L
R
D
Baker's Yeast
Sacchar. cerevisiae
P32795
747
81753
G250
L
T
Y
S
F
S
E
G
F
K
Y
I
T
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
N.A.
82.8
N.A.
88
87.8
N.A.
88.2
75.6
76.7
72.9
N.A.
44.5
43.2
40.3
51.3
Protein Similarity:
100
85.3
N.A.
86.8
N.A.
90.5
89.9
N.A.
92.8
83.5
83.6
81.6
N.A.
61.9
60.9
59.2
68.8
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
100
6.6
20
13.3
N.A.
13.3
6.6
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
26.6
26.6
N.A.
100
20
40
33.3
N.A.
20
33.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
37.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.6
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
14
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
27
0
7
0
27
7
7
0
0
34
0
7
0
7
7
% D
% Glu:
7
0
0
7
14
0
47
14
7
7
7
0
0
14
0
% E
% Phe:
0
0
0
14
14
0
14
14
7
0
14
0
14
7
0
% F
% Gly:
14
0
27
7
0
0
0
14
0
0
0
0
0
14
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
0
0
14
0
0
14
7
7
20
% I
% Lys:
0
0
7
0
7
7
0
0
7
20
27
0
7
27
7
% K
% Leu:
27
14
14
0
14
20
27
7
40
14
20
54
20
7
7
% L
% Met:
0
14
0
0
0
7
0
0
0
0
0
0
27
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% P
% Gln:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
14
54
14
14
7
0
0
7
7
0
7
7
7
7
0
% R
% Ser:
0
0
7
34
7
14
0
34
0
0
14
0
0
7
0
% S
% Thr:
0
7
20
7
0
0
0
7
0
7
0
0
7
0
34
% T
% Val:
0
0
0
0
0
27
0
7
20
14
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
0
0
0
0
0
0
0
7
14
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _