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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YME1L1 All Species: 15.15
Human Site: S250 Identified Species: 23.81
UniProt: Q96TA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96TA2 NP_055078.1 773 86455 S250 D R G S D V E S L D K L M K T
Chimpanzee Pan troglodytes XP_507710 903 100485 S380 D R G S D V E S L D K L M K T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535172 804 89574 S281 D R G S D V E S L D K L M K T
Cat Felis silvestris
Mouse Mus musculus O88967 715 80009 F240 R R T R L I L F V L L L F G I
Rat Rattus norvegicus Q925S8 715 79848 F240 R R T R L I L F V L L L F G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506440 766 85825 S243 D R G S D V E S L D K L M K T
Chicken Gallus gallus NP_001026683 722 81118 V243 L L S F F L F V L C F Y L A I
Frog Xenopus laevis NP_001084592 716 79844 L240 L R R T R L F L L V L L L I G
Zebra Danio Brachydanio rerio NP_001082983 722 79976 R240 Q R T Q E S L R R T R L I L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726263 736 80633 S242 G Y L A A A N S E D S P K S G
Honey Bee Apis mellifera XP_392703 709 79559 G243 G L R F S M D G I K F R P E T
Nematode Worm Caenorhab. elegans P54813 676 74435 E212 L M D E A K L E V E E I V D Y
Sea Urchin Strong. purpuratus XP_787399 733 80618 T240 Y M L G K D E T K K S D R F K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80983 717 77256 E241 E A K A E L E E I V H Y L R D
Baker's Yeast Sacchar. cerevisiae P32795 747 81753 G250 L T Y S F S E G F K Y I T E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 N.A. 82.8 N.A. 88 87.8 N.A. 88.2 75.6 76.7 72.9 N.A. 44.5 43.2 40.3 51.3
Protein Similarity: 100 85.3 N.A. 86.8 N.A. 90.5 89.9 N.A. 92.8 83.5 83.6 81.6 N.A. 61.9 60.9 59.2 68.8
P-Site Identity: 100 100 N.A. 100 N.A. 13.3 13.3 N.A. 100 6.6 20 13.3 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 26.6 26.6 N.A. 100 20 40 33.3 N.A. 20 33.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40.2 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. 59.6 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 14 7 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 27 0 7 0 27 7 7 0 0 34 0 7 0 7 7 % D
% Glu: 7 0 0 7 14 0 47 14 7 7 7 0 0 14 0 % E
% Phe: 0 0 0 14 14 0 14 14 7 0 14 0 14 7 0 % F
% Gly: 14 0 27 7 0 0 0 14 0 0 0 0 0 14 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 14 0 0 14 0 0 14 7 7 20 % I
% Lys: 0 0 7 0 7 7 0 0 7 20 27 0 7 27 7 % K
% Leu: 27 14 14 0 14 20 27 7 40 14 20 54 20 7 7 % L
% Met: 0 14 0 0 0 7 0 0 0 0 0 0 27 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % P
% Gln: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 54 14 14 7 0 0 7 7 0 7 7 7 7 0 % R
% Ser: 0 0 7 34 7 14 0 34 0 0 14 0 0 7 0 % S
% Thr: 0 7 20 7 0 0 0 7 0 7 0 0 7 0 34 % T
% Val: 0 0 0 0 0 27 0 7 20 14 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 7 0 0 0 0 0 0 0 7 14 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _