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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YME1L1 All Species: 13.94
Human Site: S30 Identified Species: 21.9
UniProt: Q96TA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96TA2 NP_055078.1 773 86455 S30 F H T P K N T S V S L S G V S
Chimpanzee Pan troglodytes XP_507710 903 100485 S160 F H T P K N T S V S L S G V S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535172 804 89574 S44 C K K G R P F S G G H F L L V
Cat Felis silvestris
Mouse Mus musculus O88967 715 80009 S30 F H S P K N I S V S V N T P V
Rat Rattus norvegicus Q925S8 715 79848 S30 F H S P K N I S V S V N T S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506440 766 85825 A30 F H Q P K S L A V S V T T L P
Chicken Gallus gallus NP_001026683 722 81118 A32 P K P S T T T A S T T S V Q P
Frog Xenopus laevis NP_001084592 716 79844 A30 F H T P K T A A Y F P S S A S
Zebra Danio Brachydanio rerio NP_001082983 722 79976 V30 L H S L K G S V S S N T S V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726263 736 80633 K30 Y Y S V N R T K L H G S A G A
Honey Bee Apis mellifera XP_392703 709 79559 V32 S T S F S V K V K K Q N E F K
Nematode Worm Caenorhab. elegans P54813 676 74435
Sea Urchin Strong. purpuratus XP_787399 733 80618 A30 F H S L K G G A E T T A L R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80983 717 77256 S30 L L V R A Y S S F P R V G V T
Baker's Yeast Sacchar. cerevisiae P32795 747 81753 A38 L L V Q K K W A L R S K K F Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 N.A. 82.8 N.A. 88 87.8 N.A. 88.2 75.6 76.7 72.9 N.A. 44.5 43.2 40.3 51.3
Protein Similarity: 100 85.3 N.A. 86.8 N.A. 90.5 89.9 N.A. 92.8 83.5 83.6 81.6 N.A. 61.9 60.9 59.2 68.8
P-Site Identity: 100 100 N.A. 6.6 N.A. 53.3 53.3 N.A. 40 13.3 46.6 33.3 N.A. 13.3 0 0 20
P-Site Similarity: 100 100 N.A. 20 N.A. 73.3 80 N.A. 73.3 26.6 53.3 53.3 N.A. 46.6 13.3 0 46.6
Percent
Protein Identity: N.A. N.A. N.A. 40.2 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. 59.6 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 7 34 0 0 0 7 7 7 14 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % E
% Phe: 47 0 0 7 0 0 7 0 7 7 0 7 0 14 0 % F
% Gly: 0 0 0 7 0 14 7 0 7 7 7 0 20 7 0 % G
% His: 0 54 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % I
% Lys: 0 14 7 0 60 7 7 7 7 7 0 7 7 0 7 % K
% Leu: 20 14 0 14 0 0 7 0 14 0 14 0 14 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 27 0 0 0 0 7 20 0 0 0 % N
% Pro: 7 0 7 40 0 7 0 0 0 7 7 0 0 7 14 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 7 0 0 7 0 % Q
% Arg: 0 0 0 7 7 7 0 0 0 7 7 0 0 7 7 % R
% Ser: 7 0 40 7 7 7 14 40 14 40 7 34 14 7 27 % S
% Thr: 0 7 20 0 7 14 27 0 0 14 14 14 20 0 7 % T
% Val: 0 0 14 7 0 7 0 14 34 0 20 7 7 27 14 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 7 0 0 7 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _