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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YME1L1
All Species:
13.64
Human Site:
T215
Identified Species:
21.43
UniProt:
Q96TA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96TA2
NP_055078.1
773
86455
T215
F
K
T
L
K
S
R
T
R
R
L
Q
S
T
S
Chimpanzee
Pan troglodytes
XP_507710
903
100485
T345
F
K
T
L
K
S
R
T
R
R
L
Q
S
T
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535172
804
89574
T246
F
K
T
L
K
S
R
T
R
R
L
Q
S
T
S
Cat
Felis silvestris
Mouse
Mus musculus
O88967
715
80009
A205
K
T
K
N
I
P
E
A
H
Q
D
A
F
K
T
Rat
Rattus norvegicus
Q925S8
715
79848
A205
K
T
K
N
I
P
E
A
H
Q
D
A
F
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506440
766
85825
S208
F
K
T
L
K
S
R
S
R
R
L
Q
S
T
S
Chicken
Gallus gallus
NP_001026683
722
81118
A208
I
P
E
A
H
Q
D
A
F
K
T
G
F
A
E
Frog
Xenopus laevis
NP_001084592
716
79844
D205
V
K
N
K
N
I
P
D
G
H
Q
D
A
F
K
Zebra Danio
Brachydanio rerio
NP_001082983
722
79976
K205
E
T
L
E
K
L
L
K
N
K
N
I
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726263
736
80633
A207
D
G
D
T
P
L
Q
A
E
K
L
R
R
L
L
Honey Bee
Apis mellifera
XP_392703
709
79559
F208
A
R
Q
T
Y
P
Y
F
G
W
F
K
V
M
C
Nematode Worm
Caenorhab. elegans
P54813
676
74435
V177
R
T
Y
T
D
G
F
V
K
G
L
L
S
N
G
Sea Urchin
Strong. purpuratus
XP_787399
733
80618
R205
D
P
K
K
K
K
F
R
E
T
L
G
D
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80983
717
77256
I206
A
L
I
E
D
R
G
I
G
K
G
L
G
L
H
Baker's Yeast
Sacchar. cerevisiae
P32795
747
81753
K215
S
P
L
Y
G
S
R
K
E
P
L
H
V
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
N.A.
82.8
N.A.
88
87.8
N.A.
88.2
75.6
76.7
72.9
N.A.
44.5
43.2
40.3
51.3
Protein Similarity:
100
85.3
N.A.
86.8
N.A.
90.5
89.9
N.A.
92.8
83.5
83.6
81.6
N.A.
61.9
60.9
59.2
68.8
P-Site Identity:
100
100
N.A.
100
N.A.
0
0
N.A.
93.3
0
6.6
6.6
N.A.
6.6
0
13.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
100
6.6
13.3
13.3
N.A.
26.6
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
37.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.6
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
0
0
0
27
0
0
0
14
7
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
14
0
7
0
14
0
7
7
0
0
14
7
7
0
0
% D
% Glu:
7
0
7
14
0
0
14
0
20
0
0
0
0
7
7
% E
% Phe:
27
0
0
0
0
0
14
7
7
0
7
0
20
7
0
% F
% Gly:
0
7
0
0
7
7
7
0
20
7
7
14
7
0
14
% G
% His:
0
0
0
0
7
0
0
0
14
7
0
7
0
0
7
% H
% Ile:
7
0
7
0
14
7
0
7
0
0
0
7
0
0
0
% I
% Lys:
14
34
20
14
40
7
0
14
7
27
0
7
0
14
7
% K
% Leu:
0
7
14
27
0
14
7
0
0
0
54
14
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
7
14
7
0
0
0
7
0
7
0
0
7
0
% N
% Pro:
0
20
0
0
7
20
7
0
0
7
0
0
7
0
0
% P
% Gln:
0
0
7
0
0
7
7
0
0
14
7
27
0
0
0
% Q
% Arg:
7
7
0
0
0
7
34
7
27
27
0
7
7
0
0
% R
% Ser:
7
0
0
0
0
34
0
7
0
0
0
0
34
0
27
% S
% Thr:
0
27
27
20
0
0
0
20
0
7
7
0
0
27
14
% T
% Val:
7
0
0
0
0
0
0
7
0
0
0
0
14
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _