KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YME1L1
All Species:
16.67
Human Site:
T270
Identified Species:
26.19
UniProt:
Q96TA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96TA2
NP_055078.1
773
86455
T270
A
H
Q
D
A
F
K
T
G
F
A
E
G
F
L
Chimpanzee
Pan troglodytes
XP_507710
903
100485
T400
A
H
Q
D
A
F
K
T
G
F
A
E
G
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535172
804
89574
T301
A
H
Q
D
A
F
K
T
G
F
A
E
G
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O88967
715
80009
F260
N
P
F
L
S
V
R
F
R
T
T
T
G
L
D
Rat
Rattus norvegicus
Q925S8
715
79848
F260
N
P
F
L
S
V
R
F
R
T
T
T
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506440
766
85825
T263
A
H
Q
D
A
F
K
T
G
F
A
E
G
F
L
Chicken
Gallus gallus
NP_001026683
722
81118
D263
P
G
K
G
S
F
S
D
A
V
R
F
R
T
S
Frog
Xenopus laevis
NP_001084592
716
79844
R260
K
T
P
F
L
S
V
R
F
R
T
T
S
G
L
Zebra Danio
Brachydanio rerio
NP_001082983
722
79976
T260
G
L
Y
G
L
S
K
T
P
F
L
S
V
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726263
736
80633
V262
L
K
T
I
V
V
I
V
V
F
L
G
I
F
L
Honey Bee
Apis mellifera
XP_392703
709
79559
E263
N
D
V
K
G
V
A
E
A
K
Q
E
L
S
D
Nematode Worm
Caenorhab. elegans
P54813
676
74435
R232
K
Y
S
R
L
G
G
R
L
P
K
G
V
L
L
Sea Urchin
Strong. purpuratus
XP_787399
733
80618
Y260
L
I
F
G
V
L
A
Y
L
Y
V
K
M
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80983
717
77256
K261
R
L
G
G
K
L
P
K
G
V
L
L
V
G
P
Baker's Yeast
Sacchar. cerevisiae
P32795
747
81753
S270
S
S
E
V
A
D
K
S
V
D
V
A
K
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
N.A.
82.8
N.A.
88
87.8
N.A.
88.2
75.6
76.7
72.9
N.A.
44.5
43.2
40.3
51.3
Protein Similarity:
100
85.3
N.A.
86.8
N.A.
90.5
89.9
N.A.
92.8
83.5
83.6
81.6
N.A.
61.9
60.9
59.2
68.8
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
6.6
N.A.
100
6.6
6.6
20
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
20
20
N.A.
100
20
6.6
20
N.A.
20
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
37.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.6
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
0
34
0
14
0
14
0
27
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
27
0
7
0
7
0
7
0
0
0
0
20
% D
% Glu:
0
0
7
0
0
0
0
7
0
0
0
34
0
0
0
% E
% Phe:
0
0
20
7
0
34
0
14
7
40
0
7
0
34
7
% F
% Gly:
7
7
7
27
7
7
7
0
34
0
0
14
40
14
0
% G
% His:
0
27
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
14
7
7
7
7
0
40
7
0
7
7
7
7
0
0
% K
% Leu:
14
14
0
14
20
14
0
0
14
0
20
7
7
20
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
7
14
7
0
0
0
7
0
7
7
0
0
0
0
7
% P
% Gln:
0
0
27
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
0
0
7
0
0
14
14
14
7
7
0
7
7
0
% R
% Ser:
7
7
7
0
20
14
7
7
0
0
0
7
7
7
14
% S
% Thr:
0
7
7
0
0
0
0
34
0
14
20
20
0
14
0
% T
% Val:
0
0
7
7
14
27
7
7
14
14
14
0
20
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
0
0
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _