Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YME1L1 All Species: 35.76
Human Site: T738 Identified Species: 56.19
UniProt: Q96TA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96TA2 NP_055078.1 773 86455 T738 R A K H I L K T H A K E H K N
Chimpanzee Pan troglodytes XP_507710 903 100485 T868 R A K H I L K T H A K E H K N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535172 804 89574 T769 R A K H I L K T H A K E H K N
Cat Felis silvestris
Mouse Mus musculus O88967 715 80009 T680 R A K H I L K T H A K E H K N
Rat Rattus norvegicus Q925S8 715 79848 T680 R A K H I L K T H A K E H K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506440 766 85825 T731 R A K N I L K T H A K E H K N
Chicken Gallus gallus NP_001026683 722 81118 T687 R A K N I L K T H A K E H K N
Frog Xenopus laevis NP_001084592 716 79844 T681 R A K N L L K T H A K E H K N
Zebra Danio Brachydanio rerio NP_001082983 722 79976 S687 R A K A L L K S R A K E H R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726263 736 80633 A698 L S D S Y E R A K A I L R K H
Honey Bee Apis mellifera XP_392703 709 79559 I685 S K D V E A V I N G E K I S T
Nematode Worm Caenorhab. elegans P54813 676 74435 K652 P T P A A V K K S N E T K R N
Sea Urchin Strong. purpuratus XP_787399 733 80618 E690 T L L K D S Y E R A R T I L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80983 717 77256 A690 S S A S S A A A A A A A A A A
Baker's Yeast Sacchar. cerevisiae P32795 747 81753 K714 C K G E K L D K L K T S T N T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 N.A. 82.8 N.A. 88 87.8 N.A. 88.2 75.6 76.7 72.9 N.A. 44.5 43.2 40.3 51.3
Protein Similarity: 100 85.3 N.A. 86.8 N.A. 90.5 89.9 N.A. 92.8 83.5 83.6 81.6 N.A. 61.9 60.9 59.2 68.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 86.6 66.6 N.A. 13.3 0 13.3 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. 33.3 20 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40.2 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. 59.6 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 60 7 14 7 14 7 14 7 80 7 7 7 7 7 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 14 0 7 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 7 7 0 7 0 0 14 60 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 34 0 0 0 0 54 0 0 0 60 0 7 % H
% Ile: 0 0 0 0 47 0 0 7 0 0 7 0 14 0 0 % I
% Lys: 0 14 60 7 7 0 67 14 7 7 60 7 7 60 7 % K
% Leu: 7 7 7 0 14 67 0 0 7 0 0 7 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 0 7 7 0 0 0 7 67 % N
% Pro: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 60 0 0 0 0 0 7 0 14 0 7 0 7 14 0 % R
% Ser: 14 14 0 14 7 7 0 7 7 0 0 7 0 7 0 % S
% Thr: 7 7 0 0 0 0 0 54 0 0 7 14 7 0 14 % T
% Val: 0 0 0 7 0 7 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _