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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YME1L1
All Species:
15.15
Human Site:
Y182
Identified Species:
23.81
UniProt:
Q96TA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96TA2
NP_055078.1
773
86455
Y182
T
L
R
S
S
C
L
Y
R
H
H
S
R
A
L
Chimpanzee
Pan troglodytes
XP_507710
903
100485
Y312
T
L
R
S
S
C
L
Y
R
H
H
S
R
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535172
804
89574
Y213
T
L
R
S
S
C
L
Y
R
Q
H
S
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O88967
715
80009
N172
E
R
L
V
E
A
Q
N
I
A
P
S
F
V
K
Rat
Rattus norvegicus
Q925S8
715
79848
N172
E
R
L
A
E
A
Q
N
I
A
P
S
F
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506440
766
85825
Y175
T
L
R
S
S
C
L
Y
R
Q
H
P
R
T
I
Chicken
Gallus gallus
NP_001026683
722
81118
S175
E
T
K
S
S
L
P
S
L
L
K
G
F
I
L
Frog
Xenopus laevis
NP_001084592
716
79844
E172
S
E
R
I
A
Q
M
E
K
T
A
P
S
F
M
Zebra Danio
Brachydanio rerio
NP_001082983
722
79976
E172
R
R
L
Q
G
G
F
E
G
P
V
E
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726263
736
80633
I174
G
F
K
T
D
R
S
I
E
A
E
Q
K
R
N
Honey Bee
Apis mellifera
XP_392703
709
79559
L175
D
L
T
A
I
K
N
L
F
N
N
Q
T
S
V
Nematode Worm
Caenorhab. elegans
P54813
676
74435
Q144
E
L
L
A
G
K
K
Q
K
T
S
E
G
G
V
Sea Urchin
Strong. purpuratus
XP_787399
733
80618
T172
T
K
R
A
A
S
A
T
E
L
T
T
R
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80983
717
77256
R173
I
H
T
I
S
T
E
R
T
H
F
K
E
Q
L
Baker's Yeast
Sacchar. cerevisiae
P32795
747
81753
A182
N
L
L
T
A
S
S
A
G
A
V
N
P
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
N.A.
82.8
N.A.
88
87.8
N.A.
88.2
75.6
76.7
72.9
N.A.
44.5
43.2
40.3
51.3
Protein Similarity:
100
85.3
N.A.
86.8
N.A.
90.5
89.9
N.A.
92.8
83.5
83.6
81.6
N.A.
61.9
60.9
59.2
68.8
P-Site Identity:
100
100
N.A.
86.6
N.A.
6.6
6.6
N.A.
73.3
20
6.6
0
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
100
N.A.
86.6
N.A.
6.6
13.3
N.A.
80
26.6
40
0
N.A.
20
40
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
37.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.6
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
27
20
14
7
7
0
27
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
27
7
0
0
14
0
7
14
14
0
7
14
7
7
0
% E
% Phe:
0
7
0
0
0
0
7
0
7
0
7
0
20
7
0
% F
% Gly:
7
0
0
0
14
7
0
0
14
0
0
7
7
7
7
% G
% His:
0
7
0
0
0
0
0
0
0
20
27
0
0
0
0
% H
% Ile:
7
0
0
14
7
0
0
7
14
0
0
0
0
7
7
% I
% Lys:
0
7
14
0
0
14
7
0
14
0
7
7
7
7
14
% K
% Leu:
0
47
34
0
0
7
27
7
7
14
0
0
0
0
40
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
0
0
7
14
0
7
7
7
0
0
7
% N
% Pro:
0
0
0
0
0
0
7
0
0
7
14
14
14
0
0
% P
% Gln:
0
0
0
7
0
7
14
7
0
14
0
14
0
7
0
% Q
% Arg:
7
20
40
0
0
7
0
7
27
0
0
0
34
7
0
% R
% Ser:
7
0
0
34
40
14
14
7
0
0
7
34
7
14
7
% S
% Thr:
34
7
14
14
0
7
0
7
7
14
7
7
7
14
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
14
0
0
14
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
27
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _