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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YME1L1
All Species:
14.85
Human Site:
Y306
Identified Species:
23.33
UniProt:
Q96TA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96TA2
NP_055078.1
773
86455
Y306
V
L
L
L
F
G
I
Y
G
L
L
K
N
P
F
Chimpanzee
Pan troglodytes
XP_507710
903
100485
Y436
V
L
L
L
F
G
I
Y
G
L
L
K
N
P
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535172
804
89574
Y337
V
L
L
L
F
G
I
Y
G
L
L
K
N
P
F
Cat
Felis silvestris
Mouse
Mus musculus
O88967
715
80009
V296
A
K
Q
E
L
Q
E
V
V
E
F
L
K
N
P
Rat
Rattus norvegicus
Q925S8
715
79848
V296
A
K
Q
E
L
Q
E
V
V
E
F
L
K
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506440
766
85825
Y299
V
L
L
L
L
G
I
Y
G
L
L
K
N
P
F
Chicken
Gallus gallus
NP_001026683
722
81118
E299
G
V
E
E
A
K
Q
E
L
Q
E
V
V
E
F
Frog
Xenopus laevis
NP_001084592
716
79844
E296
E
A
K
N
E
L
Q
E
V
V
D
F
L
K
N
Zebra Danio
Brachydanio rerio
NP_001082983
722
79976
A296
H
V
K
G
V
E
E
A
K
N
E
L
Q
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726263
736
80633
T298
D
P
E
E
I
N
V
T
F
E
D
V
K
G
C
Honey Bee
Apis mellifera
XP_392703
709
79559
G299
V
L
L
V
G
P
P
G
T
G
K
T
L
L
A
Nematode Worm
Caenorhab. elegans
P54813
676
74435
S268
P
F
F
H
T
A
G
S
E
F
D
E
V
L
V
Sea Urchin
Strong. purpuratus
XP_787399
733
80618
A296
T
F
D
D
V
R
G
A
D
E
A
K
N
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80983
717
77256
E297
S
C
S
G
S
E
F
E
E
M
F
V
G
V
G
Baker's Yeast
Sacchar. cerevisiae
P32795
747
81753
Y306
F
L
K
D
P
T
K
Y
E
S
L
G
G
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
N.A.
82.8
N.A.
88
87.8
N.A.
88.2
75.6
76.7
72.9
N.A.
44.5
43.2
40.3
51.3
Protein Similarity:
100
85.3
N.A.
86.8
N.A.
90.5
89.9
N.A.
92.8
83.5
83.6
81.6
N.A.
61.9
60.9
59.2
68.8
P-Site Identity:
100
100
N.A.
100
N.A.
0
0
N.A.
93.3
6.6
0
0
N.A.
0
20
0
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
0
0
N.A.
93.3
13.3
6.6
6.6
N.A.
6.6
26.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
37.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.6
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
7
7
0
14
0
0
7
0
0
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
7
0
7
14
0
0
0
0
7
0
20
0
0
0
0
% D
% Glu:
7
0
14
27
7
14
20
20
20
27
14
7
0
20
0
% E
% Phe:
7
14
7
0
20
0
7
0
7
7
20
7
0
0
34
% F
% Gly:
7
0
0
14
7
27
14
7
27
7
0
7
14
7
7
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
27
0
0
0
0
0
0
0
0
% I
% Lys:
0
14
20
0
0
7
7
0
7
0
7
34
20
14
0
% K
% Leu:
0
40
34
27
20
7
0
0
7
27
34
20
14
14
14
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
0
7
0
0
34
14
7
% N
% Pro:
7
7
0
0
7
7
7
0
0
0
0
0
0
27
14
% P
% Gln:
0
0
14
0
0
14
14
0
0
7
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
0
7
0
0
7
0
7
0
0
0
0
0
% S
% Thr:
7
0
0
0
7
7
0
7
7
0
0
7
0
0
0
% T
% Val:
34
14
0
7
14
0
7
14
20
7
0
20
14
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _